FUNCTIONAL GENOMICS

功能基因组学

• 批准号: 7171169
• 负责人: MUAYYAD R AL-UBAIDI
• 金额: $ 3.27万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7171169
• 关键词: health science research; vision

DESCRIPTION (provided by applicant): The COBRE Program will significantly improve and enhance both the quality and quantity of vision-related fundamental research in Oklahoma. This will be accomplished through the mentoring of promising junior investigators by senior faculty. The long-term goal is to develop a new generation of NIH-funded independent principal investigators who will continue to expand cutting-edge cell biology, microbiology, immunology, biochemistry, neuroscience, molecular biology, and genetics research in the vision sciences at participating Oklahoma institutions. We have identified promising junior investigators, mentors, and supportive core modules at the University of Oklahoma Health Sciences Center and Oklahoma Medical Research Foundation for funding in the initial years of the award. Both the mentors and the Project leaders have diverse, complementary scientific backgrounds and areas of expertise, making this application truly multidisciplinary in nature. In addition, we have identified PJI candidates for research projects for future competitive funding at Oklahoma State University, Langston University, the University of Oklahoma-Norman, and the University of Tulsa, and will provide start-up funds for a new vision research faculty member to be recruited by OU-Norman Department of Zoology in the second year of the award. Finally, the COBRE will establish a Scholar-in-Residence program that will provide an opportunity for faculty at other participating institutions to do research in a vision researcher laboratory. The ultimate payoff of this investment will be an enhancement of knowledge and its translation to treatment and prevention of debilitating and blinding eye diseases, which will benefit all of the people in the state, the nation, and the world. Additionally, the nature of the problems under investigation and the eye as a model of disease makes much of the proposed research immediately applicable to more generalized areas including neurodegeneration, cancer, gene therapy, pathogenesis of bacterial infectious diseases, to name only a few. Thus, in addition to intrinsic benefits to vision science, the collateral impact of vision research is substantial.

描述（由申请人提供）：COBRE计划将显著改善和提高俄克拉荷马州视觉相关基础研究的质量和数量。这将通过高级教师对有前途的初级研究人员的指导来完成。长期目标是培养新一代美国国立卫生研究院资助的独立首席研究员，他们将继续在参与俄克拉何马州机构的视觉科学领域扩展尖端细胞生物学、微生物学、免疫学、生物化学、神经科学、分子生物学和遗传学研究。