MT COBRE: HOUSEHOLD ENVIRONMENTAL RISK REDUCTION IN RURAL CHILDREN

MT COBRE：减少农村儿童的家庭环境风险

• 批准号: 7171052
• 负责人: Wade Garrison Hill
• 金额: $ 15.11万
• 依托单位: UNIVERSITY OF MONTANA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7171052
• 关键词: clinical research; environmental health; health science research potential; health science research support

DESCRIPTION (provided by applicant): The CEHS was established in 2000 with the goal of developing a nationally competitive research program to study the mechanism of human disease and environmental impacts on human disease. In order to achieve this goal three focus areas of research were selected in order to facilitate the development of a critical mass of investigators in each area and on the basis of national need and expertise within the existing faculty. These focus areas are respiratory/immunotoxicology, neurotoxicology, and genetic and cardiovascular toxicology. With the aid of startup support five talented new faculty were hired and a sixth is being recruited. State-of-the-art core facilities were established and a strong mentoring program was put into place. This COBRE application is an ideal fit to develop the new faculty, hire additional faculty to further enhance the existing faculty and to enhance the support network and the infrastructure to develop the CEHS to a nationally competitive center. The specific aims of this application are: Aim 1 Promote the development of six talented faculty through the support of individual sub-projects Aim 2 Enhance the critical mass of competitive CEHS investigators at the UM through strategic recruitment of four new faculty. Aim 3 Establish a support network for CEHS investigators that promotes infrastructure development, collaborative interaction and facilitate mentoring. Aim 4 Enhance the infrastructure for CEHS research through the acquisition of critically needed instrumentation for a shared ICPMS and Flow Cytometer; and improve facilities, i.e., clean room for ICPMS, tissue culture, small animal surgery and a bioinformatics and computational core facility. We propose that with the achievement of these specific aims that all of the investigators supported by this COBRE grant will move into R01 funding and that the an overall research environment will have been created so that the CEHS investigators will be able to obtain a NIEHS center grant, a Ph.D. training grant from the NIEHS and program project grant support.

描述（由申请人提供）：CEHS成立于2000年，目的是制定一项全国竞争性的研究计划，以研究人类疾病的机制和对人类疾病的环境影响。为了实现这一目标，选择了三个焦点研究领域，以促进每个领域的临界研究人员的发展，并基于现有教师的国家需求和专业知识。这些重点领域是呼吸/免疫毒理学，神经毒理学以及遗传和心血管毒理学。在初创企业支持的帮助下，雇用了五个才华横溢的新教师，并招募了第六个。建立了最新的核心设施，并制定了强大的指导计划。该鞋底应用程序非常适合发展新的教职员工，聘请额外的教师来进一步增强现有教师，并增强支持网络和基础设施，以将CEHS开发到全国竞争激烈的中心。 本应用程序的具体目的是： 目标1通过支持各个子项目，促进六个才华横溢的教师的发展 AIM 2通过战略招募四个新教师来增强UM竞争性CEHS调查人员的关键质量。 AIM 3为CEHS调查人员建立支持网络，以促进基础设施开发，协作互动并促进指导。 AIM 4通过获取共享ICPM和流式细胞仪的急需仪器来增强CEHS研究的基础设施；并改善设施，即ICPMS，组织培养，小动物手术以及生物信息学和计算核心设施的清洁室。 我们建议，通过实现这些具体目标，该鞋底赠款支持的所有调查人员都将进入R01资金，并将创建整个研究环境，以便CEHS的调查人员能够获得Niehs Center Grant博士学位。 NIEHS和计划项目赠款支持的培训赠款。