PSYCHOSOCIAL CORE

心理社会核心对参与临床核心的所有受试者的主要照顾者以及MCI和AD患者的家庭成员进行全面评估，并对他们进行纵向跟踪，并根据要求为他们提供咨询。常规结构化的多方面评估分为两部分：第一部分包括抑郁、焦虑、社会网络和支持以及生活质量的测量；第二部分测量家庭冲突、行为问题和照顾者反应、照顾者评价、正式和非正式支持利用等与照顾相关的具体特征。AD患者的家庭成员完成整个评估。轻度认知障碍的受试者、他们的研究伙伴和认知正常的受试者（不是照顾者）只完成这项评估的第一部分。

The Psychosocial Core conducts a comprehensive assessment of the primary caregivers of all subjects participating in the Clinical Core, and family members of those with MCI and AD, follows them longitudinally and provides them with counseling on request. The routine structured multifaceted assessment is in two parts: the first part includes measures of depression, anxiety, social network and support and quality of life; the second part measures family conflict, behavior problems and caregiver reaction, caregiver appraisal, formal and informal support utilization and other specific characteristics related to caregiving. Family members of patients with AD complete the entire assessment. Subjects with MCI, their study partners and cognitively normal subjects who are not caregivers complete only the first part of this assessment. At the conclusion of every diagnostic evaluation of the Clinical Core, counselors of the Psychosocial Core conduct conferences with the subject, primary caregiver (if appropriate) and other family members. The counseling staff is available to respond to requests for help and information, are a user-friendly resource and a link between center subjects and other center staff. They make regular follow-up telephone calls to all participants in the Psychosocial Core. Their activities facilitate recruitment of new subjects, retention of current subjects and participation of subjects in autopsy tracking and in research studies. The Psychosocial Core data is a resource for the research of the NYU Psychosocial Research Program, and for other collaborating investigators in the field. The Psychosocial Core includes a comprehensive genetic counseling and education program, which will serve the goals of the NIA-Genetics Initiative and ADCC-affiliated researchers in genetics and proteomics and provide data to extend our evaluations of psychosocial interventions to include development of effective counseling and support for concerned subjects and family members about genetic risk for AD. The large database and subject pool, to which we will continue to add new subjects and longitudinal information, will be a valuable research resource in its own right and foster the formulation of new research to improve caregiver and patient well-being.