Core--Image Analysis

核心--图像分析

• 批准号: 6901625
• 负责人: ROBERT C BURGHARDT
• 金额: $ 7.95万
• 依托单位: TEXAS A&M UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6901625
• 关键词: bioimaging /biomedical imaging; biological response modifiers; biomedical facility; cytotoxicity; electron microscopy; environmental toxicology; fluorescent dye /probe; image processing; light microscopy; molecular /cellular imaging

The Superfund Basic Research Program (SBRP) at Texas A&M University has relied heavily on the facilities and staff support available in the Image Analysis Core. This Core provides a variety of support services to SBRP investigators with major emphasis placed on assessment of the effects of a variety of biological response modifiers (including toxicants) on cells and tissues using conventional optical and electron microscopy approaches. The Core is also working with SBRP investigators to integrate advances in vital analytical cellular imaging and fluorescence probe technologies to provide some of the most sensitive approaches for analysis of the molecular mechanisms of cellular toxicity. The Image Analysis Core fills a critical need for SBRP investigators by housing state-of-the-art technologies, by providing continued maintenance and upgrades to equipment, and by offering specialized instruction and/or technical advice to investigators and their trainees. This core provides a cost-efficient and highly effective way to provide advanced imaging technologies to six different projects. Because of its extensive utilization by the individual research projects and interactions with other facilities cores, the Image Analysis Core has a strong commitment to advancing SBRP goals and provides a forum for scientific interactions between SBRP investigators.

德克萨斯A&M大学的超级基金基础研究计划（SBRP）在很大程度上依赖于图像分析核心中提供的设施和人员支持。该核心为SBRP研究人员提供各种支持服务，主要重点是使用传统的光学和电子显微镜方法评估各种生物反应调节剂（包括毒物）对细胞和组织的影响。核心还与SBRP研究人员合作，整合重要分析细胞成像和荧光探针技术的进展，为分析细胞毒性的分子机制提供一些最灵敏的方法。图像分析核心通过容纳最先进的技术，通过提供设备的持续维护和升级，以及通过提供专业指导和/或技术建议，满足SBRP调查人员的关键需求。 调查员和他们的实习生。该核心提供了一种经济高效的方式，为六个不同的项目提供先进的成像技术。由于其广泛的利用个别研究项目和与其他设施的核心互动，图像分析核心有一个坚定的承诺，以推进SBRP的目标，并提供了一个论坛SBRP研究人员之间的科学互动。