IMAGE GUIDED BRAIN TUMOR SURGERY CORE
影像引导脑肿瘤手术核心
基本信息
- 批准号:7360386
- 负责人:
- 金额:$ 39.93万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2006
- 资助国家:美国
- 起止时间:2006-08-01 至 2007-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This core project will develop the infrastructure required to translate basic technologic advances from other parts of the effort to the clinical treatment of patients with brain tumors. We will combine preoperative high-resolution functional MRI (fMRI), diffusion tensor imaging (DTI), and intraoperative electrophysiologic testing (ECS) in patients with brain tumors in eloquent cortex in order to accomplish the following general goals: 1) understand the relationship between the fMRI signal and neuronal activity; 2) develop methods which will improve the fidelity of preoperative functional brain mapping; 3) improve outcomes for patients with tumors in and around motor and language cortex; and 4) accurately assess the validity of this approach. These general goals will be supported by developing and implementing data collection and analysis tools and conducting experimental studies to accomplish the specific aims.
该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者(PI)可能从另一个NIH来源获得主要资金,因此可以在其他CRISP条目中表示。所列机构为中心,不一定是研究者所在机构。该核心项目将开发将其他部分的基本技术进步转化为脑肿瘤患者临床治疗所需的基础设施。我们将联合收割机结合术前高分辨率功能磁共振成像(fMRI)、弥散张量成像(DTI)和术中电生理测试(ECS)对功能区脑肿瘤患者进行检查,以实现以下总体目标:1)了解功能磁共振成像信号与神经元活动之间的关系; 2)开发提高术前功能脑标测保真度的方法; 3)改善运动和语言皮层及其周围肿瘤患者的预后; 4)准确评估这种方法的有效性。将通过开发和实施数据收集和分析工具以及为实现具体目标而开展实验研究来支持这些总体目标。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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ALEXANDRA J GOLBY的其他文献
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{{ truncateString('ALEXANDRA J GOLBY', 18)}}的其他基金
Quantitative Glioblastoma Margin and Infiltration Mapping with advanced diffusion-relaxation MRI
使用先进的扩散弛豫 MRI 定量胶质母细胞瘤边缘和浸润图
- 批准号:
10677545 - 财政年份:2022
- 资助金额:
$ 39.93万 - 项目类别:
Quantitative Glioblastoma Margin and Infiltration Mapping with advanced diffusion-relaxation MRI
使用先进的扩散弛豫 MRI 定量胶质母细胞瘤边缘和浸润图
- 批准号:
10390856 - 财政年份:2022
- 资助金额:
$ 39.93万 - 项目类别:
Resting-state fMRI for Language Mapping in Brain Tumor Patients
用于脑肿瘤患者语言映射的静息态功能磁共振成像
- 批准号:
9089962 - 财政年份:2015
- 资助金额:
$ 39.93万 - 项目类别:
Pre-surgical Language Mapping with fMRI using a Natural Viewing Condition
使用自然观察条件通过 fMRI 进行术前语言映射
- 批准号:
8426088 - 财政年份:2012
- 资助金额:
$ 39.93万 - 项目类别:
Pre-surgical Language Mapping with fMRI using a Natural Viewing Condition
使用自然观察条件通过 fMRI 进行术前语言映射
- 批准号:
8302886 - 财政年份:2012
- 资助金额:
$ 39.93万 - 项目类别:
Rapid Analysis of Intraoperatively Acquired DTI for Identification of Key White M
快速分析术中获得的 DTI 以识别关键白色 M
- 批准号:
8298128 - 财政年份:2011
- 资助金额:
$ 39.93万 - 项目类别:
Rapid Analysis of Intraoperatively Acquired DTI for Identification of Key White M
快速分析术中获得的 DTI 以识别关键白色 M
- 批准号:
8203349 - 财政年份:2011
- 资助金额:
$ 39.93万 - 项目类别:
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