Translational Neural Engineering: Multiple Perspectives

转化神经工程：多种视角

• 批准号: 7225665
• 负责人: PATRICK J ROUSCHE
• 金额: $ 1万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7225665
• 关键词: meeting /conference /symposium; neurons; tissue engineering; travel

DESCRIPTION (provided by applicant): The new NIH roadmap lays out a streamlined bench-to-bedside philosophy that should be applied to future biomedical research. Within the field of Neural Engineering (NE), Neurotech Reports projects that the overall worldwide market for neurotechnology products will be $3.1 billion in 2006. They predict this will reach $7.6 billion in 2010. For the typical academic researcher engaged in more traditional "basic" research, these trends represents both an opportunity and a challenge: an opportunity to more directly impact clinically relevant problems via commercialization, but a challenge to adapt from more traditional ways of practicing academic science and engineering. Although the need to shift towards a translational emphasis affects all areas of biomedical research, the field of Neural Engineering (NE) is uniquely impacted by virtue of the biologically protected status of the brain and nervous system. Not only do interventions here face some of the greatest scientific challenges of all biological systems, they can also raise serious ethical concerns. The goal of the proposed program is to provide support for a half-day special-topic symposium on Translational Neural Engineering at the annual meeting of the Biomedical Engineering Society. The symposium is titled "Translational Neural Engineering: Multiple Perspectives On Bringing Benchtop Research Into The Clinical Domain". The main objective of the special symposium is to consider the question: What constitutes a viable model for translational research in the field of Neural Engineering? Implicit in the formulation of an answer to this question is the need to: define translational NE research, identify successful and unsuccessful strategies within NE, and highlight areas of need and opportunity within NE. To achieve this, a diverse and broad- ranging list of speakers has been assembled. Successful academic science and engineering researchers who have had translational research success, the clinicians who have been involved in the process, a bioethicist and a representative from a government funding agency have already agreed to participate. The symposium is particularly well-suited for educating students (who constitute 65% of the >2100 attendees) and junior faculty. The long-term objective of the symposia is to equip traditional researchers with the skills, methodologies and mindset for success in translational neural engineering. A white paper on translational neural engineering will be submitted as a manuscript to Journal of Neural Engineering after the meeting. The proposed symposia becomes relevant to public health when the long- term objectives are met and traditional research engineers are adequately trained to navigate the waters of successful translational research in neural engineering. This will effectively provide a smoother/faster path to market for the clinical application of exciting neural engineering technological breakthroughs aimed at improving diagnostic and therapeutic success for diseases of the nervous system. The proposed symposia titled "Translational Neural Engineering: Multiple Perspectives On Bringing Benchtop Research Into The Clinical Domain" becomes relevant to public health when the long-term objectives are met and traditional research engineers are adequately trained to navigate the waters of successful translational research. This will effectively provide a smoother/faster path to market for the clinical application of exciting technological breakthroughs aimed at improving diagnostic and therapeutic success for diseases of the nervous system.

描述（由申请人提供）：新的NIH路线图列出了一个精简的从实验室到床边的哲学，应该应用于未来的生物医学研究。在神经工程（NE）领域，神经技术报告预测，2006年神经技术产品的全球市场总额将达到31亿美元。他们预测这一数字在2010年将达到76亿美元。对于从事更传统的“基础”研究的典型学术研究人员来说，这些趋势既是机遇也是挑战：通过商业化更直接地影响临床相关问题的机会，但从实践学术科学和工程的更传统方式中适应的挑战。虽然转向翻译重点的需要影响了生物医学研究的所有领域，但神经工程（NE）领域由于大脑和神经系统的生物保护状态而受到独特的影响。这里的干预措施不仅面临着所有生物系统中最大的科学挑战，而且还可能引发严重的伦理问题。该计划的目标是为生物医学工程学会年会上为期半天的翻译神经工程专题研讨会提供支持。研讨会的标题是“转化神经工程：将台式研究带入临床领域的多个视角”。特别研讨会的主要目标是考虑这个问题：什么构成了神经工程领域转化研究的可行模型？隐含在制定一个答案，这个问题是需要：定义翻译NE研究，确定成功和不成功的战略内NE，并强调需要和机会内NE领域。为实现这一目标，汇集了一份多样化和范围广泛的发言者名单。成功的学术科学和工程研究人员谁有转化研究的成功，临床医生谁参与了这个过程中，生物伦理学家和政府资助机构的代表已经同意参加。研讨会特别适合教育学生（占2100多名与会者的65%）和初级教师。研讨会的长期目标是为传统研究人员提供在转化神经工程中取得成功的技能，方法和心态。一份关于转化神经工程的白色论文将在会后作为手稿提交给《神经工程杂志》。当长期目标得到满足，传统的研究工程师得到充分的培训，能够在神经工程成功转化研究的沃茨中航行时，拟议的研讨会就变得与公共卫生相关。这将有效地为激动人心的神经工程技术突破的临床应用提供更顺畅/更快的市场路径，旨在提高神经系统疾病的诊断和治疗成功率。拟议的专题讨论会题为“转化神经工程：将台式研究带入临床领域的多个视角”，当长期目标得到满足，传统的研究工程师得到充分的培训，以驾驭成功的转化研究的沃茨时，将与公共卫生相关。这将有效地为旨在提高神经系统疾病诊断和治疗成功率的令人兴奋的技术突破的临床应用提供更顺畅/更快的市场途径。