Characterization of novel bacteria membrane stress response system

细菌面临着源源不断的环境压力，这些压力会损害细胞，而细胞膜是一个脆弱但关键的组成部分，需要保护。一种名为IM30蛋白的蛋白质家族被认为是膜损伤的第一反应者，通过一种鲜为人知的机制来挽救膜功能。这些都是古老的蛋白质，也在植物的叶绿体中发现，它们也以不同的方式与膜相互作用，它们在一系列生物技术有用的微生物中的功能可以为生物制造提供新的途径，生产更坚固的底盘。

Bacteria face a constant stream of environmental stresses that damage the cell and the cell membrane is a fragile but critical component that needs protection. A family of proteins called IM30 proteins are thought to play important roles as 'first responders' to membrane damage, working through a poorly studied mechanism to rescue membrane function. These are ancient proteins found also in the chloroplasts of plants where they also interact with membranes in different ways and their function in a range of biotechnologically useful microbes could provide novel routes to producing more robust chassis for biomanufacturing.