2007 Cellular Osmoregulation: Sensors, Tranducers & Regulators Gordon Research Co

描述(由申请人提供)： 第三届戈登关于细胞渗透调节：传感器、传输器和调节器的会议将于2007年6月3日至8日在法国奥索伊斯的保罗·朗之万中心举行。会议为研究细胞体积变化的传感机制以及用于调节这些体积的无机和有机渗透调节物质的运输和调节提供了一个论坛。此外，还讨论了渗透分子与水、细胞大分子和膜的物理-化学相互作用，并结合生物学研究表明，许多有机渗透分子保护生物分子免受非渗透干扰。会议通过涵盖生命的范围，从微生物到藻类，从植物到动物，以及从生物物理化学到膜生理学再到基因调控的多层次研究，促进了跨学科的协同作用。对渗透紊乱作出反应的细胞渗透调节是与NIDDK任务相关的许多问题背后的一个基本现象。许多参与者是由NIH资助的，许多人从事与人类肾脏和疾病相关的渗透调节方面的工作。此外，了解渗透物质的性质对于探索使用这些溶质保存生物分子、治疗蛋白质折叠疾病和作物的遗传修改至关重要。通过9个科学会议，组织者计划了一个高度跨学科的项目，展示来自世界各地的研究人员的最新研究。2007年大会将 以人类疾病的渗透失衡为新主题，从一位主旨演讲者开始。除了被邀请的发言者和讨论领袖外，申请参加会议的人将在海报会议上介绍他们目前的工作，或者，如果被组委会选中，将在适当的会议上进行简短的演讲。这些评选将以提交的海报摘要为基础，以作品的价值和实现性别、年龄和少数群体地位多样化的目标为基础。第三次会议的主要目标是继续扩大渗透调节所有领域的研究人员的参与，特别是将原本永远不会相遇的研究人员聚集在一起。将特别注意增加初级研究人员的参与：研究生、博士后和处于职业生涯早期阶段的研究人员。这些年轻的人口是新思想和新技术的重要来源。在会议的各个方面，主办方都在努力促进妇女、少数群体和残疾人的参与。

DESCRIPTION (provided by applicant): The third Gordon Conference on Cellular Osmoregulaton: Sensors, Transporters and Regulators will be held June 3-8, 2007 at the Centre Paul Langevin in Aussois, France. The conference provides a forum for the study of mechanisms involved in the sensing of cell volume changes and transport and regulation of inorganic and organic osmolytes used to adjust those volumes. In addition, the physical-chemical interactions of osmolytes with water and cellular macromolecules and membranes are addressed, in concert with biological studies showing that many organic osmolytes protect biomolecules from non-osmotic disturbances. The conference fosters interdisciplinary synergy by encompassing the scope of life, from microorganisms to algae to plants to animals, and multiple levels of investigation from biophysical chemistry to membrane physiology to gene regulation. Cellular osmoregulation in response of osmotic disturbances is a basic phenomenon underlying many of the issues that pertain to NIDDK's mission. Many of the participants are funded by NIH, and many work on aspects of osmoregulation related to human kidneys and diseases. Moreover, understanding the properties of osmolytes is crucial to studies exploring the use of these solutes for preserving biomolecules, treating protein-folding diseases, and genetic modifications of crop plants. Through 9 scientific sessions, the organizers have planned a highly interdisciplinary program of presentations about the most current research by investigators from around the world. The 2007 conference will feature a new theme of osmotic imbalances in human diseases, beginning with a keynote speaker. In addition to invited speakers and discussion leaders, those applying to the conference will present their current work in poster sessions, or, if selected by the Organizing Committee, in a short talk in the appropriate session. These selections will be based on submitted poster abstracts, based on the merit of the work and on the goal of achieving diversity in terms of gender, age and minority status. A primary goal of this third conference is to continue widening the involvement of researchers from all areas of osmoregulation, in particular bringing together investigators who would otherwise never encounter each other. Particular attention will be paid to increasing the participation of junior researchers: graduate students, postdocs, and investigators in the early stages of their careers. This younger population is an important source of new ideas and techniques. In all aspects of the conference, the organizers are working to promote the involvement of women, minorities and people with disabilities.