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中文摘要
翻译
描述(由申请人提供):本提案为2007年关节炎研究会议申请部分资金,这是我们的第六届两年一次的会议,该会议将由关节炎基金会、美国风湿病学会和国家关节炎、肌肉骨骼和皮肤疾病研究所联合赞助。会议将于2007年4月20日至22日在佐治亚州亚特兰大常青万豪会议中心举行。主要目的是通过一个多学科的会议环境,促进讨论新的技术方法和发起新的科学合作,增加年轻研究人员的教育和网络机会。所有北美地区的关节炎研究学员将被邀请参加。我们还将邀请根据其专门知识和兴趣选定的高级研究人员,他们最有可能为会议的激励和富有成效的环境作出贡献并从中受益。参加人数限制为400人。全体讲座将由有成就的杰出调查人员提供,他们还将主持会议和讲习班,并在会议期间与受训者互动。全体会议,题为。关节炎医学的翻译:从长凳到床边。,将致力于提供NIH扩展转化努力计划的概述,并讨论几个例子,在这些例子中,基本的分子和细胞观察已成功地发展成为风湿病的新颖、安全、有效的治疗方法。基础科学专题讨论会将专门讨论…关节中的信号和调节,以及细胞内通路如何促进关节发育,以及在其他情况下这些组织的疾病相关破坏。临床科学研讨会将重点讨论这一主题。炎症性疾病的新观点。会有特价。临床结果研究研讨会。,并将举办8个讲习班,供选定的学员介绍他们的研究,其中包括:类风湿性关节炎的发病机制和相关的小鼠模型;狼疮的临床治疗措施及发病机制关节软骨生物学与组织工程修复策略风湿病的临床结果和流行病学;组织工程与基因治疗;风湿病研究的新兴技术;细胞外基质与炎症的调节;SLE和自身免疫的发病机制此外,将有三次海报会议,所有剩下的学员将有机会展示他们的作品。总的来说,会议的中心目标是在非正式的气氛中提供一个互动的会议,促进对关节炎发病机理和相关肌肉骨骼疾病的科学基础的全面讨论。会议将努力促进学员和来自非常不同背景的资深科学家之间有意义的互动,讨论当前的工作,并激发新的倡议和协作互动。
英文摘要
DESCRIPTION (provided by applicant): This proposal requests partial funding for Arthritis Research Conference, 2007, our sixth biennial conference, which will be held under the joint sponsorship of the Arthritis Foundation, the American College of Rheumatology, and the National Institute of Arthritis, Musculoskeletal and Skin Diseases. The meeting will be held on April 20-22, 2007 at the Evergreen Marriott Conference Center, Atlanta GA. The primary aim is to enhance the educational and network opportunities of young investigators, through a multi-disciplinary conference environment that is conducive to discussions of new technical approaches and the initiation of novel scientific collaborations. All arthritis research trainees in North America will be invited to attend. We will also invite selected senior researchers, identified based on their expertise and interests, who will most likely contribute to, and benefit from the stimulating and productive environment of the Conference. Participation will be limited to 400 attendees. Plenary lectures will be provided by accomplished distinguished investigators, who will also chair sessions and workshops, and interact with trainees during the Conference. The plenary session, entitled .Translation in Arthritis Medicine: Bench to the Bedside., will be devoted to providing an overview of NIH plans for extending translational efforts, and talks on several examples in which basic molecular and cellular observations have been successfully developed into novel and safe and effective therapies in the rheumatic diseases. The Basic Science Symposium will be devoted to the topic of .Signaling and regulation in the Joint, and how intracellular pathways contribute to joint development, and in other settings disease-associated destruction of these tissues. The Clinical Sciences Symposium will focus on the topic .New Perspectives on Inflammatory Disease. There will be a special .Clinical Outcomes Research Symposium., as well as eight workshops will be held for selected trainees to present their research, which will include: Pathogenesis of RA and related murine models; Clinical measures and pathogenesis of Lupus; Biology of articular cartilage and tissue engineering repair strategies; Clinical outcomes and epidemiology of rheumatic diseases; Tissue engineering and gene therapy; Emerging technologies for the study of rheumatic diseases; Regulation of extracellular matrix and Inflammation; and SLE and pathogenesis of autoimmunity. In addition, there will be three poster sessions, at which all remaining trainees will have an opportunity to present their work. Overall, the central goal of the conference is to provide an interactive meeting in an informal atmosphere that facilitates comprehensive discussion of the scientific basis of arthritis pathogenesis and related musculoskeletal diseases. The Conference will strive to promote meaningful interactions between trainees and senior scientists from very diverse backgrounds to discuss current work, as well as stimulate new initiatives and collaborative interactions.
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Core 1 - Research Technology Core
Project 2: Microbiome pathobionts and Lupus pathogenesis
Project 2: Microbiome pathobionts and Lupus pathogenesis
Core 1 - Research Technology Core
国内基金
海外基金
Autoimmune diseases therapies: variations on the microbiome in rheumatoid arthritis
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data