9th International Meeting on Human Genome Variation and Complex Genome Analysis

描述（由申请人提供）：该提案寻求NHGRI资助，以部分支持美国学员和来自代表性不足群体的初级教员参加第九届人类基因组变异和复杂基因组分析国际会议（HGV 2007），该会议将于2007年9月6日至9日在巴塞罗那附近的Meli Sitges酒店举行。HGV 2007会议特别及时，因为人类基因组变异研究领域进展非常快，HapMap第一阶段项目于2005年10月完成，HapMap第二阶段结果预计将在不久的将来发表。人们也越来越认识到，基因组的拷贝数多态性和结构变异是人类进化的重要标志和人类疾病的原因。此外，目前正在进行许多全基因组研究，这些研究的结果将在本次会议举行时提交。在HGV 2007中，我们将致力于人类变异研究的新兴领域的大量报道，并汇集不同领域的研究人员，以促进合作，并推动该领域进一步沿着。这次会议的独特之处在于，它汇集了人类变异研究许多领域的顶尖研究人员，从将极大地改变该领域的全新技术，到不同类型人类变异产生的机制，再到考虑到拷贝数变异的HapMap时代遗传研究的新统计方法，基于比较基因组变异分析的分子进化研究，以及人类变异研究的社会和伦理意义。HGV 2007会议的目标是提出一个为期三天的计划，其中将包括基因组学，群体遗传学，分子进化，统计遗传学，分子流行病学和伦理学方面的国际知名专家的演讲。如下所述，会议将专门讨论基因组结构（包括结构变异）、全基因组分析、比较遗传学和群体遗传学、表达和表观遗传变异、全基因组分析的统计工具、信息学和数据库、变异分析技术和战略、人类基因组学中的表型和伦理、法律的和社会问题。

DESCRIPTION (provided by applicant): This proposal seeks NHGRI funding to partially support US trainees and junior faculty members from under-represented groups to attend the 9th International Meeting on Human Genome Variation and Complex Genome Analysis (HGV2007) to be held at the Meli Sitges Hotel near Barcelona from September 6-9, 2007. The HGV2007 meeting is particularly timely because the field of human genome variation research is moving very fast, with the completion of the HapMap Phase I Project in October 2005 and the anticipated publication of the HapMap Phase II results in the near future. There is also increasing recognition that copy number polymorphisms and structural variations of the genome are important signatures of human evolution and causes of human diseases. In addition, many whole-genome studies are currently under way and results from these studies will be ready for presentation by the time this meeting is held. In HGV2007, we will devote substantial coverage of the emerging areas of human variation research and bring together investigators in diverse fields to promote collaborations and move the field even further along. The unique feature of this meeting is that it brings together top researchers in the many areas of human variation research, from radically new technologies that will change the field dramatically, to the mechanisms of how different types of human variations came about, to new statistical approaches for genetic studies in the HapMap era that take into account copy number variations, to the study of molecular evolution based on comparative genome variation analysis, and to the social and ethical implications of human variation research. The objective of the HGV2007 meeting is to present a three day program, which will include presentations by internationally known experts in genomics, population genetics, molecular evolution, statistical genetics, molecular epidemiology, and ethics. As detailed below, meeting sessions will be devoted to genome structure (including structural variations), whole genome analysis, comparative and population genetics, expression and epigenetic variations, statistical tools for whole genome analysis, informatics and databases, and variation analysis technologies and strategies, phenotype and ethical, legal and social issues in human genomics.