Nutrient Control of Gene Expression & Cell Signaling

描述(由申请人提供)： 这项申请是为了部分支持FASE B夏季会议“基因表达和细胞信号的营养控制”。该会议每两年举行一次，请为2005年、2007年和2009年的会议提供支助。2005年会议将于7月30日至8月4日在亚利桑那州图森市举行。这次会议的目标是汇聚来自许多不同学科的科学家，他们对营养和非营养饮食因素对基因表达和细胞信号的调控感兴趣。饮食在人类健康和疾病中起着至关重要的作用，了解饮食成分影响细胞生物学和生理学的潜在分子机制是至关重要的。大会将有八个口头会议、两个海报会议和开幕式和主旨演讲。会议的初始会议围绕以下中心主题组织：通过营养物质，如葡萄糖和脂肪酸，通过维生素和矿物质，以及通过植物化学物质和外源生物物质对基因表达的分子调控。稍后的会议将集中讨论代谢流量控制、mTOR在营养感知中的作用、能量平衡与肥胖、卡路里限制与衰老等“热门话题”。此外，一个致力于新兴技术的会议将向与会者介绍可用于研究营养问题的最新技术进步。每堂课将有四位特邀演讲者和从特邀摘要中选出的另外一到两位演讲者。已作出努力，让年轻的科学家、妇女和少数群体参加整个会议。将为研究生和博士后研究员的最佳海报演示文稿颁发奖项，以鼓励他们参与。这一主题的跨学科性质意味着营养学家、分子和细胞生物学家、生物化学家和生理学家之间的互动对这一重要领域的进展至关重要。通过这次会议，我们希望为科学家之间就与营养和健康有关的共同概念问题进行富有成效的信息交流提供环境。

DESCRIPTION (provided by applicant): This application is for partial support for the FASEB Summer Conference on "Nutrient Control of Gene Expression & Cell Signaling." This conference is held biennially and support is requested for meetings in 2005, 2007 and 2009. The 2005 conference will be held in Tucson, Arizona, from July 30 - August 4. The goal of this conference is to bring together scientists from many different disciplines interested in the regulation of gene expression and cell signaling by nutrient and non-nutrient dietary factors. Diet plays a critical role in human health and disease and understanding the underlying molecular mechanisms by which dietary components influence cell biology and physiology is essential. The conference will have eight oral sessions, two poster sessions and opening and keynote lectures. The initial sessions of the meeting are organized around the central themes of molecular regulation of gene expression by nutrients, such as glucose and fatty acids, by vitamins and minerals, and by phytochemicals and xenobiotics. Later sessions will focus on 'hot topics' such as metabolic flux control, the role of mTOR in nutrient sensing, energy balance and obesity, and caloric restriction and aging. In addition, a session dedicated to emerging technologies will introduce attendees to recent technological advances that can be applied to studying nutritional problems. Each session will feature four invited speakers and one or two additional speakers selected from invited abstracts. Efforts have been made to include younger scientists, women and minorities throughout the meeting. Awards will be given to the top poster presentations by graduate students and postdoctoral fellows to encourage their participation. The interdisciplinary nature of this topic means that interactions between nutritionists, molecular and cell biologist, biochemists and physiologists are critical to progress in this important area. Through this conference, we hope to provide the environment for fruitful exchange of information between scientists with common conceptual problems related to nutrition and health.