The mechanisms of portable negative pressure wound therapy on wounds

负压疗法长期以来一直被认为是伤口治疗中有价值的工具，可以控制渗出，提供屏障功能，支持伤口愈合过程，并帮助护理患者。新型负压设备，如Pico，提供便携式负压治疗，使患者和临床团队在使用时具有更大的灵活性。它通过其专利技术具有独特的行动模式，使治疗能够超越伤口向更广泛的区域提供治疗，包括周围伤口。该设备工作的生物学机制尚不清楚，可能有助于破译哪些患者对该设备反应最好，区分适应症，重要的是确定可以进一步推进以改善伤口愈合的新机制。

Negative pressure therapy has long been established as valuable tool in wound therapy to control exudate, provide barrier function, support wounds through the healing process and help with nursing care of patients. New negative pressure devices such as the PICO provides portable negative pressure therapy enabling the patient and clinical teams far greater flexibility in use. It has a unique mode of action through its proprietary technology enabling delivery of therapy beyond the wound to wider regions including the peri wound. The biological mechanisms by which the device works remains unclear and may help decipher which patients best respond to the device, stratify indications, and importantly identify novel mechanisms that could be further advanced to improve on wound healing.