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Genetic validation of Stat3 as a tractable pharmacological target in gastrointestinal disease

Genetic validation of Stat3 as a tractable pharmacological target in gastrointestinal disease
Stat3 作为胃肠道疾病中易于处理的药理学靶点的基因验证
批准号:
nhmrc : 1069024
负责人:
A/Pr Frederic Hollande
金额:
$39.14万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-12-31

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中文摘要
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英文摘要
Cancers of the stomach and the colon are a major health burden. One of the central signaling molecules that drives these cancers is called Stat3. Here we propose to use a novel strain of mice that allows us to experimentally dial down the amount of Stat3 protein and hence to predict how effective a future anti-Stat3 cancer drug will be.
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Volatile Anaesthesia and Cancer Recurrence
  • 批准号:
    nhmrc : 1147498
  • 项目类别:
    Project Grants
  • 资助金额:
    $43.78万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Frederic Hollande
  • 依托单位:
Targeting Colon Cancer with Jak inhibitors
  • 批准号:
    nhmrc : 1064987
  • 项目类别:
    Project Grants
  • 资助金额:
    $43.13万
  • 财政年份:
    2014
  • 负责人:
    A/Pr Frederic Hollande
  • 依托单位:
Novel Therapeutics for Colon Cancer treatment
  • 批准号:
    nhmrc : GNT1064987
  • 项目类别:
    Project Grants
  • 资助金额:
    $62.56万
  • 财政年份:
    2014
  • 负责人:
    A/Pr Frederic Hollande
  • 依托单位:
Elucidating the role of claudin-2 in tumour initiation and metastasis development from colorectal cancer: consequence for tumour relapse
  • 批准号:
    nhmrc : 1049561
  • 项目类别:
    Project Grants
  • 资助金额:
    $26.6万
  • 财政年份:
    2013
  • 负责人:
    A/Pr Frederic Hollande
  • 依托单位:
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