Multidisciplinary Training Program in Lung Disease

描述(由申请人提供)： 拟议的更新是为了继续目前的肺部疾病多学科培训计划(HL-07185)，该计划提供对呼吸系统重要的基础和临床科学方面的培训。该计划利用心血管研究所工作人员的基础和临床研究技能，以及加州大学旧金山分校其他教员的专门技能。这笔资助将容纳总共15名博士后实习生(每年约8名新实习生)，包括医学博士和博士。主要计划是在P接受者和审查委员会的密切监督下进行实际研究体验，审查委员会是根据实习生的实验方法选择的。这些方法包括适用于分子、细胞、组织、器官、整个动物、临床或种群水平的学科。此外，还相当重视为个人在学术医学领域的各种职业做准备而创造的特殊教育机会。该教育计划提供基础科学(如蛋白质组学和人类遗传学)、生物统计学、流行病学研究设计、医学经济学和科学行为伦理学方面的特别课程、小组会议和研讨会。重点放在专门为个别受训人员设计的个人指导上。正在增加新的设施和教员，以进一步巩固现代生物学、生物信息学和严格的临床研究的学科。人们相当重视研究和培训中的多学科互动，以及在科学需要领域发展和实施学术事业，特别是在那些以前没有得到重视的领域。我们计划的新兴增长领域包括细菌和病毒发病机制、免疫学、用于研究的针对疾病的多机构临床网络、人类遗传学和分子流行病学、强调重症监护医学的调查，以及人口水平调查技术的进一步发展。另一个重要的重点领域是招募和留住该方案中任职人数不足的少数群体和妇女。我们的多学科项目过去和未来的成功是建立在广泛不同的教职员工之间的密切合作基础上的，包括临床和面向医生的科学家，并将这种合作转化为研究培训和职业发展的协调方法。

Description (provided by applicant): The proposed renewal is for a continuation of the present Multidisciplinary Training Program in Lung Disease (HL-07185), which provides training in basic and clinical sciences important to the respiratory system. The program draws on the basic and clinical research skills of the staff of the Cardiovascular Research Institute and on the specialized skills of other members of the faculty of UCSF. The grant is to accommodate a total of fifteen postdoctoral Trainees (approximately eight new Trainees per year), including both MD's and PhD's. The main program is an actual research experience under the close supervision of a Preceptor and a review committee selected on the basis of the experimental approaches of the Trainee. These approaches include disciplines applicable at the molecular, cellular, tissue, organ, whole animal, clinical, or population levels. In addition, considerable emphasis is placed on special educational opportunities that have been created to prepare individuals for a diverse range of careers in academic medicine. The educational program provides special courses, small group conferences and seminars in basic sciences (such as proteomics and human genetics), biostatistics, epidemiological study design, medical economics, and ethics of scientific conduct. Emphasis is placed on personal instruction specifically designed for individual Trainees. New facilities and faculty are being added to further solidify the disciplines of modern biology, bioinformatics, and rigorous clinical research. Considerable emphasis has been placed on multidisciplinary interaction in research and training, and developing and implementing academic careers in areas of scientific need, especially in those previously underemphasized. Emerging areas of growth in our program include bacterial and viral pathogenesis, immunology, multi-institutional disease-specific clinical networks for research, human genetics and molecular epidemiology, investigation emphasizing critical care medicine, and the further development of population-level investigational techniques. An additional important area of emphasis is the recruitment and retention of underrepresented minorities and women in the program. The past and future success of our multidisciplinary program is predicated on a close collaboration among a widely diverse faculty, including clinical and bench-oriented scientists and translating this collaboration to a coordinated approach to research training and career development.