Immunology Physician Scientist Training Grant

这是一份NIH T32机构培训拨款申请，用于贝勒的一个新项目 医学院专注于将医生培训为该学科的研究人员 免疫学的。受训人员将从一大批优秀人才中招募和挑选出来 申请参加ACGME/RRC批准的贝勒过敏和过敏双轨培训计划 免疫学和风湿学。将选出一名学员参加拟议的T32 训练计划每年进行三年的严格科学训练后 完成一年的过敏/免疫学和风湿学临床培训。十五 终身教职员工是经过精心挑选的导师，基于他们的 精益求精的研究和教学。学员将参加研究生院的课程和 贝勒的NIH K30支持临床研究的内科科学家课程，以获得 基础科学和免疫学知识的健全基金，开展的原则 临床研究，以及研究的道德行为。实习生将全面 指导以假设为导向的研究、手稿的准备和出版， 在国家会议上的介绍、赠款提案的准备、教学技能和 辅导和学术生涯发展。导师是从40多位导师中挑选出来的 贝勒新的多学科炎症生物学中心的教员，以及 为调查人员提供高度互动的关键群体，培训对象多样化，包括 研究生、医学生、博士后和医学博士后。导师提供 细胞因子结构和功能、趋化因子生物学、黏附方面的培训机会 分子，信号转导和信号终止，基因激活， 金属蛋白酶与组织重塑、细胞免疫学和免疫调节 小鼠炎症模型的建立及有效流行病学和临床试验工具的设计 结果分析。培训计划的目标是培养免疫内科医生 将成为未来学术领袖的科学家。

This is an NIH T32 institutional training grant application for a new program at Baylor College of Medicine focused on the training of physicians as investigators in the discipline of immunology. Trainees will be recruited and selected from a large pool of outstanding applicants to the ACGME/RRC approved Baylor dual track training programs in allergy and immunology and in rheumatology. One trainee will be selected to enter the proposed T32 training program each year for three years of rigorous scientific training after they have completed one year of clinical training in allergy/immunology and rheumatology. Fifteen tenure track faculty have been carefully selected to serve as mentors, based on their excellence in research and teaching. Trainees will enroll in graduate school courses and Baylor's NIH K30 supported physician scientist course in clinical investigation to acquire a sound fund of knowledge in basic science and immunology, the principles of conducting clinical research, and the ethical conduct of research. Trainees will be comprehensively mentored in hypothesis driven research, preparation and publication of manuscripts, presentations at national meetings, preparation of grant proposals, skills for teaching and mentoring, and academic career development. The mentors are selected from over 40 faculty within the new multidisciplinary Biology of Inflammation Center at Baylor, and provide a highly interactive critical mass of investigators with diverse trainees comprised of graduate students, medical students, PhD postdocs and MD postdocs. Mentors provide training opportunities in cytokine structure and function, chemokine biology, adhesion molecules, signal transduction and termination of signaling, gene activation, metalloproteases and tissue remodeling, cellular immunology and immunoregulation, murine models of inflammation, and design of valid tools for epidemiology and clinical trial outcome analysis. The goal of the training program is to develop immunology physician scientists who will serve as the academic leaders of the future.