Training in Microbial Pathogenesis

描述（由申请人提供）：拟议的培训计划将继续为选定的博士生（博士）提供微生物发病机制方面的指导。将作出重大努力，吸引和培养来自代表性不足的种族/族裔群体的候选人。博士研修生的必修课程（核心课程）以思考发病机制为主；它从基础生物化学和细胞生物学课程以及基础免疫学课程开始。它还包括研讨会课程，向学生介绍发病机理的文献。在第二年的细菌遗传生理学和病毒学课程之后，微生物发病机理和流行病学课程。此时，受训者将在学院实验室开始发病机理研究，并将继续进行发病机理研讨会课程。这些课程将偏向于从发病机制文献中举出例子。所有受训者都必须出席大约每周举行两次的所有发病机制研讨会；博士后和高年级学生参加此类研讨会。资格考试是基于“美国国立卫生研究院类型”的研究计划。课程是专门为博士生设计的，与布法罗大学（UB）的其他专业学生分开教授。实验室研究从博士预科学习的第一年开始，至少在不同的实验室进行三次轮换。受训者的主要经验是研究导致论文，这通常需要至少三年。除了实验室和杂志社的工作外，博士后还参加一些选定的研究生课程。成功的主要标准是洞察力、独立性、实验室技能、展示工作的能力以及对他人工作和安置的批判性分析。微生物发病机制系每年组织三次国家/区域会议，学员参加这些会议并在会上介绍他们的工作。受训人员还在每周的科学交流系列研讨会上介绍他们的工作。布法罗大学在生物医学科学方面有丰富的补充教育经验，可供所有希望利用这所主要大学校园的规模和范围的学员使用。

DESCRIPTION (provided by applicant): The proposed training program will continue to provide instruction for selected predoctoral students (PhD) in Microbial Pathogenesis. Substantial efforts will be made to attract and nurture candidates from underrepresented racial/ethnic groups. The required course work for predoctoral trainees (the core curriculum) is designed to focus thinking on pathogenesis; it starts with fundamental biochemistry and cell biology courses and a basic immunology course. It also includes seminar courses, in which students are introduced to the pathogenesis literature. In the second year, courses in bacterial genetics and physiology and virology courses are followed by microbial pathogenesis and epidemiology courses. At this time, trainees will have started pathogenesis research in a faculty laboratory, and will continue with pathogenesis seminar courses. These courses will be taught with a bias towards examples from the pathogenesis literature. All trainees are required to be present at all pathogenesis seminars, held approximately twice/week; postdoctoral fellows and senior students present in such seminars. The qualifying examination is based on an "NIH-type" research proposal. Courses are specifically designed for PhD students and are taught separately from those given to other professional students at the University at Buffalo (UB). Laboratory research begins in the first year of predoctoral study with at least three rotations in different laboratories. The major experience for trainees is research leading to a dissertation, for which at least three years is normally required. In addition to laboratory and journal club work, postdoctoral fellows attend selected graduate courses. The chief criteria for success are insight, independence, laboratory skills, ability to present work and critical analysis of the work of others and placement. Three times yearly, the microbial pathogenesis faculty organize national/regional meetings, which trainees attend and at which they present their work. Trainees also present their work in a weekly scientific exchange seminar series. UB has a wealth of supplementary educational experiences in biomedical sciences available for all trainees who wish to take advantage of the size and scope of this major University campus.