Neuroimaging Training in Pediatrics & Brain Development

描述(申请人提供)：这项培训拨款的目的是教育成像科学家在研究正常和不正常的大脑发育、评估和评估涉及儿童中枢神经系统的疾病以及研究这些疾病如何影响正常的大脑发育和恢复(即重组和可塑性)方面应用先进的神经成像方法。神经成像现在是，也将继续是研究正常和异常大脑发育的最重要的工具之一。我们认为，目前儿科神经科学领域训练有素的影像研究人员数量不足以满足未来学术项目和行业的需求。该培训计划的主要目标是开始提供一批在成像科学和发育中的大脑生物学方面都接受过良好培训的成像研究人员。提出了两个级别的培训。第一个项目将培训辛辛那提大学生物医学工程系的3名博士前研究生，他们将参加基础和高级成像方法、解剖学和生理学、胚胎学、生物化学、研究方法(研究设计和生物统计学)、发展生物学和计算机科学的课程。他们的论文将直接关注成像在发育神经科学中的应用。培训持续时间约为5年，最终将获得生物医学工程硕士和博士学位，重点是儿科神经成像。第二期将作为一个综合培训机会，将涉及4名博士后研究员的培训，这些博士后研究员来自儿科的神经成像、精神病学、心理学、神经病学、康复、生物化学和基础神经科学等不同学科，专注于其子专业中的神经成像应用。这种方法的目标是集成跨多个儿科神经科学学科的成像，并与辛辛那提儿童医院医学中心(CCHMC)的成像研究中心(IRC)的跨学科目标一致。这些奖学金的有效期为两年。这一培训计划的教员将来自各种儿科神经科学学科；目前所有人都活跃在研究中，涉及儿科神经成像的某些方面，因为它适用于儿童中枢神经系统疾病或发育。我们预计，由于这种跨学科的方法，该项目的学员将在学术和行业的职业生涯中取得良好的成功。

DESCRIPTION (provided by applicant): The goal of this training grant is to educate imaging scientists in the application of advanced neuroimaging methods in the study of normal and abnormal brain development, the assessment and evaluation of diseases involving the central nervous system in children, and the study of how those diseases affect normal brain development and recovery (i.e. reorganization and plasticity). Neuroimaging is now, and will continue to be, one of the most important tools available for the study of both normal and abnormal brain development. We believe that currently a pool of well-trained imaging researchers in pediatric neuroscience does not exist in sufficient numbers to meet future demands in academic programs and in industry. The primary goal of this training program is to begin to provide a pool of imaging researchers well trained in both the imaging sciences as well as the biology of the developing brain. Two levels of training are proposed. The first will involve the training of 3 predoctoral graduate students from the Department of Biomedical Engineering at the University of Cincinnati who will take classes in basic and advanced imaging methods, anatomy and physiology, embryology, biochemistry, research methods (Research Design and Biostatistics), developmental biology and computer science. Their dissertation will focus directly on imaging applications in developmental neuroscience. The duration of training will be approximately 5 years and will culminate in both a M.S. and Ph.D. in Biomedical Engineering with a focus on pediatric neuroimaging. The second will serve as an integrative training opportunity and will involve the training of 4 postdoctoral fellows pulling from a variety of disciplines including neuroimaging, psychiatry, psychology, neurology, rehabilitation, biochemistry and basic neuroscience in pediatrics to focus on neuroimaging applications in their subspecialty. The goal of such an approach is to integrate imaging across multiple pediatric neuroscience disciplines, and is consistent with the interdisciplinary goals of the Imaging Research Center (IRC) at Cincinnati Children's Hospital Medical Center (CCHMC). These fellowships will be for a two-year period. Faculty of this training program will pull from a variety of pediatric neuroscience disciplines; all currently active in research which involves some aspect of pediatric neuroimaging as it applies to childhood CNS disease or development. We expect that trainees from this program will have good success in moving on to careers in both academia and industry as a result of this interdisciplinary approach.