Physiological activation and targets of calcium signaling in muscle

肌肉中钙信号的生理激活和目标

• 批准号: FT140101309
• 负责人: Prof Bradley Launikonis
• 金额: $ 53.25万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT140101309
• 关键词: Physiological; activation; targets; calcium; signaling

The skeletal muscle fibre is a highly specialised cell for the rapid delivery of calcium to elicit contraction, required for posture, movement and thus one's independence. Calcium is also a signal for other purposes, such as triggering other processes within the muscle for its own maintenance. These calcium signals are poorly understood. This project aims to determine when the calcium signals are turned on during normal muscle activity and what the end result of the signals is for the muscle.

骨骼肌纤维是一种高度专门化的细胞，用于快速输送钙以引起收缩，这是姿势，运动和独立性所需的。钙也是一种用于其他目的的信号，例如触发肌肉内的其他过程以进行自身维护。对这些钙信号的了解很少。该项目旨在确定正常肌肉活动期间钙信号何时开启，以及信号的最终结果是什么。