CELL BIOLOGY AND CELL IMAGING CORE

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The Cell Biology and Cell Imaging Core is a new Core that has evolved from aspects of two previous cores, the Cell Biology Core which focused on live cell imaging, and the Histochemistry/Morphology Core which focused on cell structure and the localization of biological molecules in fixed cells. The Cell Imaging Core is designed to provide information on the localization of molecules in live and fixed cells and their changes over time and in response to physiological and pathophysiological perturbation. It is centered around microscopic imaging and quantitative analysis of digital information obtained primarily by last scanning confocal microscopy (LSCM) and multiwavelength fluorescence imaging although traditional electron microscopy of fixed and embedded specimens is also available for fine structure analysis.