Systems and Integrative Biology Training Grant

描述（由申请人提供）：本申请要求继续支持一个培训计划，提供研究生攻读博士学位。在系统和综合生物学方面接受过广泛的国家或最先进的培训。 学生将学习并应用基因组学，生物信息学，蛋白质组学以及细胞和分子生物学的工具和方法来研究集成系统和器官生物学。该计划以分子与综合生理学系为中心，因为其长期致力于综合生物学，但学生将从第一年进入生物医学科学（PIBS）的综合门户课程，并可以参加多个博士学位。程序.学员将获得两年的支助。潜在的申请人池是所有申请PIBS的学生，包括谁来密歇根州学习综合生物学和那些谁进入未定，然后被吸引到综合生物学的学生。培训包括正式的课程和研讨会，教学和研究经验，在密歇根大学的各个部门的教师。所有学生将参加系统和综合生理学，细胞生理学，细胞和分子生物学，遗传学和生物化学的研究生课程。额外的课程由学生根据他/她的兴趣选择。生物学研究的综合方法通过在本科生理学课程中教授会议部分来加强。学生们还参加每周的学生研究研讨会，他们预计将批判性地评估他们的同龄人的演示文稿。这种广泛的培训进一步加强了每个学生在学习的第二年结束时参加书面初步考试，需要了解功能，从细胞和分子水平到生物体，包括环境和生物体之间的相互作用。拟议的培训的一个独特的方面是，所有学生将有两个论文共同主席，而不是更传统的单把椅子，其中至少有一个人将在细胞和分子生物学的最新技术和一个是一个综合生物学家的学校。培训教师由44名杰出的科学家组成，他们都是细胞和分子或系统和综合生物学方面的专家，并致力于培训个人回答综合生理相关问题。

DESCRIPTION (provided by applicant): This application requests continuing support for a training program which provides graduate students studying for the Ph.D. degree with broad state-or-the-art training in Systems and Integrative Biology. Students will learn and apply tools and approaches of genomics, bioinformatics, proteomics as well as cell and molecular biology to the study of integrated systems and organismic biology. The program is centered in the Department of Molecular & Integrative Physiology because of its longstanding commitment to integrative biology but students will enter from an initial year in a combined gateway Program in Biomedical Sciences (PIBS) and can be enrolled in multiple Ph.D. programs. Trainees will be supported for two years. The potential applicant pool is all students applying to PIBS and includes both students who come to Michigan to study integrative biology and those who enter undecided and are then drawn to integrative biology. The training includes formal coursework and seminars, teaching, and research experiences with faculty in a variety of departments at the University of Michigan. All students will take graduate level courses in Systems and Integrative Physiology, Cell Physiology, Cellular and Molecular Biology, Genetics and Biochemistry. Additional courses are selected by the student in accordance with his/her interests. The integrative approach to the study of biology is reinforced by teaching conference sections in an undergraduate physiology course. Students also participate in weekly student research seminars in which they are expected to critically evaluate the presentations of their peers. This broad training is further reinforced by each student taking a written preliminary examination at the end of the second year of study that requires an understanding of function, from the cellular and molecular level to that of the organism including interactions between the environment and the organism. A unique aspect of the proposed training is that all students will have two dissertation co-chairs, rather then the more traditional single chair, at least one of whom will be schooled in the most recent techniques in cellular and molecular biology and one being an integrative biologist. The training faculty consists of 44 outstanding scientists all of whom are expert in either cellular and molecular or systems and integrative biology and committed to training individuals to answer questions of integrative physiological relevance.