Implementation of a pancreas knowledgebase

胰腺知识库的实施

• 批准号: 8722027
• 负责人: JOHN A WILLIAMS
• 金额: $ 4.7万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-15 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8722027
• 关键词: Affect; American; Antibodies; Area; Bioinformatics; Biology; Book Chapters; Cellular Structures; Communities; Copyright; Country; Data Security; Development; Directories; Disease; Electronics; Exocrine pancreas; Foundations; Funding; Future; General Population; Health; Individual; Internet; Joints; Knowledge; Libraries; Link; Maintenance; Malignant neoplasm of pancreas; Medicine; Michigan; Mus; Names; Occupations; Pancreas; Pancreatic Diseases; Pancreatitis; Pathology; Pathway interactions; Peer Review; Printing; Procedures; PubMed; Publications; Published Comment; Published Directory; Reading; Request for Applications; Request for Proposals; Research; Research Methodology; Research Personnel; Resources; Schools; Site; Societies; Source; Structure; Surveys; System; Universities; Update; Viral Vector; Work; cell type; cost; data integrity; design; digital; editorial; interest; journal article; knowledge base; meetings; member; tool; web page

DESCRIPTION (provided by applicant): This proposal requests support to construct and implement an electronic resource for information on the exocrine pancreas. This pancreas knowledge base will be called "The Pancreapedia". It is designed to compile and curate knowledge on the exocrine pancreas, its component cell types and its diseases including pancreatitis and pancreatic cancer. It will also encourage new research and promote sharing of methods and research tools. It will contain six major divisions: Reviews, Pathways, Molecule Pages, Cell Structure, Research Tools, and People (Directory, community bulletin board). Content will be divided into "Entries" and "Posts". Entries will be invited or submitted and managed by Editors and an Editorial Board that will carry out peer review. After acceptance, staff will format and mount the finished copy which will be accompanied by a version number, date and digital object identifier (DOI). Material will be hyperlinked to other relevant areas in the site and to sites outside such as PubMed and NCBI. Material can be updated when ever appropriate but when content is changed it will be given a new date and version number. Posts will be entered directly onto a structured web page by individuals who have registered as members and will include Directory Listings, Research Tools (mouse lines, viral vectors, antibodies) and Comments. Comments can be made on all entries and will be accompanied by the commenter's name and picture. The site is constructed using Drupal as the content management system with the aim of minimizing the work of putting up new content. It will be mounted on a server at the University of Michigan Library (MPublishing) which will be the Publisher and responsible for data security and integrity. All content will be open access with the copyright remaining with the author. After establishment of the resource funds to cover the cost of maintenance and putting up new content will come from The American Pancreatic Association and other organizations (Societies and Foundations) interested in pancreatic research.

描述（由申请人提供）：该提案要求支持构建和实施胰腺外分泌信息的电子资源。这个胰腺知识库将被称为“胰腺百科全书”。它的目的是汇编和策划外分泌胰腺，其组成细胞类型和疾病，包括胰腺炎和胰腺癌的知识。它还将鼓励开展新的研究，促进方法和研究工具的共享。它将包含六个主要部分：评论，途径，分子页面，细胞结构，研究工具和人员（目录，社区公告板）。内容将分为“文章”和“帖子”。将邀请或提交，并由编辑和编辑委员会进行同行评审管理。验收后，工作人员将格式化和安装完成的副本，将伴随着版本号，日期和数字对象标识符（DOI）。材料将被超链接到网站中的其他相关区域以及PubMed和NCBI等外部网站。材料可以在适当的时候更新，但当内容发生变化时，将给出新的日期和版本号。帖子将由注册为会员的个人直接输入到一个结构化的网页上，其中包括目录列表，研究工具（鼠标线，病毒载体，抗体）和评论。评论可以对所有条目，并将伴随着评论者的姓名和图片。该网站使用Drupal作为内容管理系统，旨在最大限度地减少发布新内容的工作。它将安装在密歇根大学图书馆（MPublishing）的服务器上，该图书馆将是出版商并负责数据的安全性和完整性。所有内容都将开放访问，版权归作者所有。在建立资源基金，以支付维护和提出新的内容的成本将来自美国胰腺协会和其他组织（协会和基金会）感兴趣的胰腺研究。