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中文摘要
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描述(由申请者提供):本提案请求支持建立和实施一个关于胰腺外分泌信息的电子资源。这个胰腺知识库将被称为“胰腺百科全书”。它旨在汇编和整理关于胰腺外分泌、其组成细胞类型及其疾病(包括胰腺炎和胰腺癌)的知识。它还将鼓励新的研究,并促进方法和研究工具的共享。它将包括六个主要部分:综述、途径、分子页面、细胞结构、研究工具和人员(目录、社区公告栏)。内容将分为“条目”和“帖子”。参赛作品将由编辑和编辑委员会邀请或提交和管理,编辑委员会将进行同行审查。验收后,工作人员将格式化并安装完成的副本,该副本将附有版本号、日期和数字对象标识符(DOI)。材料将被超链接到网站内的其他相关区域和外部网站,如PubMed和NCBI。材料可以在适当的时候更新,但当内容发生变化时,它将被赋予新的日期和版本号。帖子将由注册为会员的个人直接输入到结构化网页上,并将包括目录列表、研究工具(鼠标线、病毒载体、抗体)和评论。所有参赛作品都可以发表评论,并附上评论者的姓名和图片。该网站是使用Drupal作为内容管理系统来构建的,目的是最大限度地减少发布新内容的工作量。它将安装在密歇根大学图书馆(MPublish)的服务器上,该服务器将是出版商,负责数据安全和完整性。所有内容都将开放访问,版权归作者所有。在资源基金建立后,用于支付维护费用和提供新内容的资金将来自美国胰腺协会和其他对胰腺研究感兴趣的组织(学会和基金会)。
英文摘要
DESCRIPTION (provided by applicant): This proposal requests support to construct and implement an electronic resource for information on the exocrine pancreas. This pancreas knowledge base will be called "The Pancreapedia". It is designed to compile and curate knowledge on the exocrine pancreas, its component cell types and its diseases including pancreatitis and pancreatic cancer. It will also encourage new research and promote sharing of methods and research tools. It will contain six major divisions: Reviews, Pathways, Molecule Pages, Cell Structure, Research Tools, and People (Directory, community bulletin board). Content will be divided into "Entries" and "Posts". Entries will be invited or submitted and managed by Editors and an Editorial Board that will carry out peer review. After acceptance, staff will format and mount the finished copy which will be accompanied by a version number, date and digital object identifier (DOI). Material will be hyperlinked to other relevant areas in the site and to sites outside such as PubMed and NCBI. Material can be updated when ever appropriate but when content is changed it will be given a new date and version number. Posts will be entered directly onto a structured web page by individuals who have registered as members and will include Directory Listings, Research Tools (mouse lines, viral vectors, antibodies) and Comments. Comments can be made on all entries and will be accompanied by the commenter's name and picture. The site is constructed using Drupal as the content management system with the aim of minimizing the work of putting up new content. It will be mounted on a server at the University of Michigan Library (MPublishing) which will be the Publisher and responsible for data security and integrity. All content will be open access with the copyright remaining with the author. After establishment of the resource funds to cover the cost of maintenance and putting up new content will come from The American Pancreatic Association and other organizations (Societies and Foundations) interested in pancreatic research.
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