NIDA Clinical Trials Network - New York Node

描述(由申请人提供)： CTN的纽约节点是一个由学术中心、临床项目以及当地和地区性机构组成的联盟，在研究、培训、服务交付、政策制定、资金和宣传成瘾障碍方面有着卓有成效的合作记录。该财团提供了一批丰富的人才，并可以获得纽约市、纽约州和该地区的大量临床和政策资源。这些研究人员、提供者和政策制定者共同拥有广泛的大规模临床试验专业知识、广泛的研究兴趣、独特的治疗能力以及广泛的服务和政策经验。在过去五年中，纽约节点建立了有效的内部和外部工作关系，它为国家CTN基础设施做出了贡献，它建立了坚实和灵活的当地基础设施，它作为牵头节点和参与节点有效地执行了协议。NY节点在2002年3月组织NIDA的NY混合会议中发挥了关键作用，并成功地与新兴的地方联盟合作，促进了CTN创新的传播和采用。NY Node提供商和研究人员参与了三项研究(START、ADHD和处方阿片类止痛剂依赖协议)的规划和开发，这三项研究将是NIDA在未来几年的优先事项，我们的CTP都处于测试和引入医疗干预的有利地位。根据CTN五年的经验以及我们对CTN取得的成就和面临的挑战所作的评估，我们提出了本建议。我们的总体专题办法充分利用了国家技术网络和节点迄今取得的成就，并应对了未来的挑战。我们引入了新的调查人员和专业知识，我们为CTN研究描述了一个增强的科学到实践的模型，我们扩大了与州和地方政府机构的关系以实现这一点，我们提出了一个在这个框架内工作的研究概念。主题包括与初级保健提供者接触，扩大相关成果，与能够分担研究费用和促进采用的机构合作，以及解决补偿和护理组织制度问题。我们的研究理念建立在这些主题之上，以扩大CTN的覆盖范围，并增强CTN研究产生影响并在更广泛的水平上改善医疗保健的可能性。

DESCRIPTION (provided by applicant): The New York Node of the CTN is a consortium of academic centers, clinical programs and local and regional agencies with a long track record of fruitful collaboration in research, training, service delivery, policy-making, funding and advocacy for the addictive disorders. The consortium offers a rich array of human talent and has access to vast clinical and policy resources in NY City, NY State and regionally. Together, these investigators, providers and policy-makers have extensive large-scale clinical trials expertise, a broad range of research interests, unique treatment capacity and extensive services and policy experience. Over the past five years the NY Node has built effective internal and external working relationships, it has contributed to the national CTN infrastructure, it has built a solid and flexible local infrastructure and it has effectively implemented protocols as a Lead Node and as a Participating Node. The NY Node played a key role in organizing NIDA's NY Blending Conference in March, 2002, and has successfully worked with emerging local coalitions to foster dissemination and adoption of CTN innovations. NY Node providers and researchers are involved in planning and developing three studies (START, ADHD and prescription opiate analgesic dependence protocols) that will be of high priority for NIDA over the next few years and our CTPs are all well positioned to test and introduce medical interventions. The present proposal is contextualized by five years of CTN experience and by our assessment of the accomplishments of, and challenges facing, the CTN. Our overall thematic approach capitalizes on CTN and Node accomplishments to-date and addresses challenges for the future. We bring in new investigators and expertise, we describe an enhanced science-to-practice model for CTN studies, we expand relationships with state and local government agencies to enable this, and we propose a research concept that works within this framework. Themes include reaching out to primary-care providers, extending relevant outcomes, partnering with agencies that can share study costs and foster adoption, and addressing systems of reimbursement and organization of care. Our research concept builds on these themes to extend the reach of the CTN and to enhance the likelihood that CTN studies will have impact and lead to improved healthcare on a broader level.