NIDA CLINICAL TRIALS NETWORK - NYC EAST SIDE NODE

即将成立的NIDA全国药物滥用临床试验网络(CTN)的使命是通过(1)加快治疗研究的步伐，在现实生活治疗环境中测试小型对照研究的结果，以及(2)通过传播和培训加快新治疗技术的社区治疗计划的实施，来提高全国药物滥用治疗的质量。CTN的具体目标包括在一系列治疗环境和临床人群中开展药理学、行为学和实践研究领域的研究；就如何最好地将以科学为基础的发现转化为临床实践进行研究；鼓励社区治疗机构与学术研究人员之间的合作；以及评估实施新的治疗模式对健康和系统的影响。纽约市东区(NYC-ES)节点将为这一总体使命做出贡献：(1)在成瘾研究、培训和治疗方面的领导地位，(2)广泛的临床试验专门知识和广泛的临床能力，(3)最先进的临床试验数据管理系统和专门知识，(4)在传播和评估成瘾治疗培训材料方面的领导作用，以及(5)在以下领域对网络作出贡献的独特能力：(A)健康服务和健康结果研究；(B)与吸毒成瘾脆弱性有关的遗传学和药物遗传学；(C)中央数据管理。NYC-ES Node是一个由学术和临床研究人员/提供者组成的联盟，他们在成瘾障碍的研究、培训和临床服务提供方面有着卓有成效的长期合作记录。以社区为基础的治疗方案(CTP)的特点是方案和治疗模式的多样性，并为10,000多名患者提供了广泛的诊断、种族和性别多样性的临床服务。地区研究和培训中心(RRTC)的组成部分包括(1)洛克菲勒大学成瘾疾病研究实验室及其康奈尔附属项目，(2)纽约大学医学院酒精中毒和药物滥用部门，(3)纽约大学和内森·克莱恩研究所具有广泛大规模临床试验经验的研究人员小组，以及(4)内森·克莱恩研究所的流行病学和卫生服务研究实验室。

The mission of the to-be-established NIDA National Drug Abuse Clinical Trials Network (CTN) is to improve the quality of drug abuse treatment nationally by (1) accelerating the pace of treatment research, testing findings from small controlled studies in real-life treatment settings, and (2) accelerating community-treatment-program implementation of new treatment technologies via dissemination and training. Specific CTN objectives include conducting studies in the areas of pharmacological, behavioral and practice research in a range of treatment settings and clinical populations; conducting studies on how best to translate science-based findings into clinical practice; encouraging collaboration between community treatment facilities and academic researchers; and assessing the health and systems impact of the implementation of new treatment modalities. The New York City East Side (NYC-ES) Node will contribute the following to this overall mission: (1) leadership in addiction research, training and treatment, (2) broad clinical trials expertise and extensive clinical capacity, (3) a state-of the-art clinical trials data management system and expertise, (4) leadership in dissemination and evaluation of addiction treatment training material, and (5) unique capacity to contribute to the network in the following areas (a) health services and health outcomes research, (b) genetics and pharmacogenetics related to vulnerability to drug addiction, (c) central data management. The NYC-ES Node is a consortium of academic and clinical investigators/providers who have a longstanding track record of fruitful collaboration in research, training, and clinical service delivery for the addictive disorders. The Community-based Treatment Programs (CTPs) are characterized by programmatic and treatment-model diversity, and provide access to an overall clinical population of more than 10,000 patients with extensive diagnostic, ethnic and gender diversity. Regional Research and Training Center (RRTC) components include (1) the Rockefeller University Laboratory for the Study of Addictive Disease and its Cornell-affiliated programs, (2) the NYU School of Medicine Division of Alcoholism and Drug Abuse; (3) a group of NYU and Nathan Kline Institute investigators with extensive large scale clinical trials experience; and (4) the Epidemiology and Health Services Research Laboratory at the Nathan Kline Institute.