NIDA CLINICAL TRIALS NETWORK - NYC EAST SIDE NODE

NIDA 临床试验网络 - 纽约东区节点

• 批准号: 6071490
• 负责人: JOHN P ROTROSEN
• 金额: $ 220万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-02-20 至 2005-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6071490
• 关键词: behavioral /social science research tag; clinical research; clinical trials; community; cooperative study; data management; drug abuse therapy; genetic susceptibility; health care personnel education; health care service evaluation; health science research analysis /evaluation; health services research tag; human subject; human therapy evaluation; information dissemination

The mission of the to-be-established NIDA National Drug Abuse Clinical Trials Network (CTN) is to improve the quality of drug abuse treatment nationally by (1) accelerating the pace of treatment research, testing findings from small controlled studies in real-life treatment settings, and (2) accelerating community-treatment-program implementation of new treatment technologies via dissemination and training. Specific CTN objectives include conducting studies in the areas of pharmacological, behavioral and practice research in a range of treatment settings and clinical populations; conducting studies on how best to translate science-based findings into clinical practice; encouraging collaboration between community treatment facilities and academic researchers; and assessing the health and systems impact of the implementation of new treatment modalities. The New York City East Side (NYC-ES) Node will contribute the following to this overall mission: (1) leadership in addiction research, training and treatment, (2) broad clinical trials expertise and extensive clinical capacity, (3) a state-of the-art clinical trials data management system and expertise, (4) leadership in dissemination and evaluation of addiction treatment training material, and (5) unique capacity to contribute to the network in the following areas (a) health services and health outcomes research, (b) genetics and pharmacogenetics related to vulnerability to drug addiction, (c) central data management. The NYC-ES Node is a consortium of academic and clinical investigators/providers who have a longstanding track record of fruitful collaboration in research, training, and clinical service delivery for the addictive disorders. The Community-based Treatment Programs (CTPs) are characterized by programmatic and treatment-model diversity, and provide access to an overall clinical population of more than 10,000 patients with extensive diagnostic, ethnic and gender diversity. Regional Research and Training Center (RRTC) components include (1) the Rockefeller University Laboratory for the Study of Addictive Disease and its Cornell-affiliated programs, (2) the NYU School of Medicine Division of Alcoholism and Drug Abuse; (3) a group of NYU and Nathan Kline Institute investigators with extensive large scale clinical trials experience; and (4) the Epidemiology and Health Services Research Laboratory at the Nathan Kline Institute.

即将成立的NIDA国家药物滥用临床试验网络（CTN）的使命是通过以下方式提高全国药物滥用治疗的质量：（1）加快治疗研究的步伐，在现实生活中的治疗环境中测试小型对照研究的结果，以及（2）通过传播和培训加速社区治疗计划实施新的治疗技术。 CTN的具体目标包括在一系列治疗环境和临床人群中开展药理学、行为学和实践研究领域的研究;研究如何最好地将基于科学的研究成果转化为临床实践;鼓励社区治疗设施和学术研究人员之间的合作;评估实施新治疗模式对健康和系统的影响。纽约市东区（NYC-ES）节点将为这一总体使命做出以下贡献：（1）在成瘾研究、培训和治疗方面的领导地位，（2）广泛的临床试验专业知识和广泛的临床能力，（3）最先进的临床试验数据管理系统和专业知识，（4）在成瘾治疗培训材料的传播和评估方面的领导地位，和（5）在以下领域为网络作出贡献的独特能力：（a）保健服务和保健结果研究，（B）与易吸毒成瘾性有关的遗传学和药物遗传学，（c）中央数据管理。NYC-ES节点是学术和临床研究者/提供者的联盟，他们在成瘾性疾病的研究，培训和临床服务提供方面有着长期的富有成效的合作记录。 以社区为基础的治疗方案（CTP）的特点是方案和治疗模式的多样性，并提供了一个超过10,000名患者的广泛的诊断，种族和性别多样性的整体临床人群。 区域研究和培训中心（RRTC）的组成部分包括（1）洛克菲勒大学成瘾性疾病研究实验室及其康奈尔大学附属项目，（2）纽约大学医学院酒精中毒和药物滥用分部;（3）一组纽约大学和内森克莱恩研究所的研究人员，具有广泛的大规模临床试验经验;及（4）Nathan Kline Institute的流行病学及卫生服务研究实验室。