Glutamate - adenosine interactions and drug-seeking

谷氨酸-腺苷相互作用和药物寻求

• 批准号: nhmrc : 566736
• 负责人: A/Pr Kevin Pfleger
• 金额: $ 37.21万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/glutamate-adenosine-interactions-drug-seeking/96516
• 关键词: Glutamate; adenosine; interactions; drug; seeking

Substance abuse is a significant social and economic burdern upon Australian societies and on societies around the world. Treatment remains problematic due to the multi-layer nature of the disease, difficulties with treatment compliance and less than ideal treatment regimes. The present study aims to improve treatments for alcohol and drug abuse using a polypharmacy or multiple therapy approach, using pre-clinical models to determine the utility of this approach.

药物滥用是澳大利亚社会和世界各地社会的重大社会和经济负担。由于该疾病的多层次性质、治疗依从性困难以及不太理想的治疗方案，治疗仍然存在问题。本研究旨在使用多种药物或多种治疗方法来改善酒精和药物滥用的治疗，并使用临床前模型来确定这种方法的效用。