School-Based Intervention to Prevent Metabolic Syndrome

预防代谢综合症的校本干预

• 批准号: 7272436
• 负责人: Alan M Delamater
• 金额: $ 22.94万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7272436
• 关键词: Adolescence; Age; Age-Years; Area; Behavior; Behavioral; Beta Cell; Blood Pressure; Child; Child health care; Childhood; Clinical; Condition; Data; Development; Diet; Dietary intake; Disease; Early Diagnosis; Eating; Educational Curriculum; Educational Materials; Environment; Family; Feedback; Female; Focus Groups; Frequencies; Functional disorder; Gender; Health Promotion; Health behavior; Health behavior change; Health education; Home environment; Incidence; Insulin Resistance; Intervention; Knowledge; Life Style; Measures; Mediating; Metabolic; Metabolic syndrome; Minority; Modeling; Modification; Natural History; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Outcome; Outcome Measure; Overweight; Parents; Pattern; Physical activity; Pilot Projects; Prevention; Psychosocial Factor; Randomized; Rate; Recruitment Activity; Research; Risk; Risk Factors; School-Age Population; Schools; Second Degree Relative; Social Marketing; Testing; Time; Treatment Efficacy; Weight maintenance regimen; Youth; base; blood lipid; design; elementary school; ethnic minority population; improved; intervention program; modifiable risk; obesity prevention; prevent; programs; sedentary; type 2 diabetes in children

DESCRIPTION (provided by applicant): More than 25% of children are at risk of or overweight and this increases metabolic risk factors for type 2 diabetes; ethnic minority children are at even higher risk for being overweight and developing type 2 diabetes. Prevention of metabolic syndrome and type 2 diabetes should begin by prevention of overweight in childhood. We will develop a school-based multi-component intervention program to promote healthy lifestyles in young children in order to prevent overweight and metabolic syndrome. The intervention will promote healthful eating and physical activity through social marketing, a health education curriculum, modification of the school environment, and family programming at the school so that parents can reinforce behavioral changes and model these change in the home environment. Focus groups will first be conducted at one school to refine the intervention for acceptability and cultural appropriateness and then the intervention approach and materials will be pre-tested in additional focus groups. A pilot study will then be conducted in order to test the hypothesis that the school-based intervention for children in grades K-1 will reduce their risk for overweight and metabolic syndrome. We will recruit 60 children from each of two additional schools and randomize one school to receive the 12 month intervention and the other school to receive a control condition consisting of children's health risk feedback and educational materials for parents. Primary outcomes are measures of overweight and metabolic risk, including estimates of insulin resistance. Secondary outcomes include measures of dietary intake, physical activity, blood pressure, and blood lipids. Children will be assessed at baseline and after six and 12 months of the intervention. The results from this study will contribute new knowledge concerning school-based interventions to improve health behaviors so that overweight and metabolic syndrome can be prevented in ethnic minority children. These findings will provide the preliminary feasibility and efficacy data needed for the development and submission of a subsequent R18 application. Approximately 30% of ethnic minority children are overweight and at increased risk for developing metabolic syndrome and eventually type 2 diabetes. Prevention of metabolic syndrome and type 2 diabetes should begin by prevention of overweight in childhood. We will develop and test the efficacy of a school-based multi- component intervention program to promote healthy lifestyles in young ethnic minority children in order to prevent overweight and metabolic syndrome.

描述（由申请人提供）：超过25%的儿童有患2型糖尿病的风险或超重，这增加了2型糖尿病的代谢风险因素;少数民族儿童超重和患2型糖尿病的风险更高。预防代谢综合征和2型糖尿病应从预防儿童期超重开始开始。我们将制定一项以学校为基础的多成分干预计划，以促进幼儿的健康生活方式，以预防超重和代谢综合征。干预措施将通过社会营销、健康教育课程、学校环境改造和学校的家庭规划来促进健康饮食和体育活动，以便父母能够加强行为变化，并在家庭环境中模仿这些变化。首先在一所学校进行焦点小组讨论，以改进干预措施的可接受性和文化上的适当性，然后在其他焦点小组中对干预措施的方法和材料进行预先测试。然后将进行一项试点研究，以检验这一假设，即对K-1年级儿童进行以学校为基础的干预将降低他们超重和代谢综合征的风险。我们将从另外两所学校各招募60名儿童，随机选择一所学校接受12个月的干预，另一所学校接受控制条件，包括儿童的健康风险反馈和家长教育材料。主要结果是超重和代谢风险的测量，包括胰岛素抵抗的估计。次要结果包括饮食摄入量、体力活动、血压和血脂的测量。儿童将在基线和干预6个月和12个月后进行评估。本研究的结果将为改善少数民族儿童的健康行为，预防超重和代谢综合征提供新的知识。这些发现将为后续R18应用的开发和提交提供所需的初步可行性和有效性数据。大约30%的少数民族儿童超重，患代谢综合征和最终患2型糖尿病的风险增加。预防代谢综合征和2型糖尿病应从预防儿童期超重开始开始。我们将制定和测试以学校为基础的多成分干预计划的有效性，以促进少数民族儿童的健康生活方式，以预防超重和代谢综合征。