Chronic Prostatitis Collaborative Research Network

慢性前列腺炎合作研究网络

• 批准号: 7235697
• 负责人: ANTHONY J SCHAEFFER
• 金额: $ 23.7万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-05 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7235697
• 关键词: Blinded; Chronic Prostatitis; Clinical; Clinical Investigator; Clinical Trials; Collection; Contracts; Data Coordinating Center; Diagnostic; Disease; Enrollment; Joints; Long-Term Effects; Manuals; National Institute of Diabetes and Digestive and Kidney Diseases; Operative Surgical Procedures; Patients; Pharmaceutical Preparations; Placebos; Protocols documentation; Prunus africana; Randomized; Recruitment Activity; Research; Sabal serrulata; Sampling; Scientist; Standards of Weights and Measures; Symptoms; Therapy Clinical Trials; U-Series Cooperative Agreements; chronic pelvic pain; lower urinary tract symptoms; member; men; placebo controlled study; prospective; prostatitis; response

DESCRIPTION (provided by applicant): This proposal is in response to an invitation for a cooperative agreement (contract) for one of ten clinical centers to collaboratively establish, perform, maintain and evaluate multiple therapeutic trials, either sequentially or concurrently for treatments of prostatitis through the collection and analysis of information and clinical samples from patients with the disorder. The long-term objective will be attained by: 1. Developing a protocol(s) and manual of operations through the joint efforts of the Steering Committee consisting of members of the clinical centers, data coordinating center, and the NIDDK project scientist. The investigator from the clinical centers in conjunction with the data coordinating center, will have responsibility in developing the protocol(s). 2. Recruiting and admitting patients into the study who have met agreed upon diagnostic entry criteria, have standard demographic information, symptoms related to prostatitis and who will provide clinical samples collected at established intervals will be enrolled. Northwestern's proposed clinical trial is to conduct a prospective multi-center randomized blinded placebo controlled trial of Saw palmetto (SP) or Pygeum africanum (PA) or placebo in patients with symptoms of chronic pelvic pain syndrome (CPPS). Because of the widespread use of these medications for the treatment of CPPS and lower urinary tract symptoms in men, and the neat total lack of well-performed studies on the efficacy and long-term effects, a placebo controlled trial is needed as defined using the CPCRN criterion.

描述（由申请人提供）：