Chronic Prostatitis Collaborative Research Network
慢性前列腺炎合作研究网络
基本信息
- 批准号:7415414
- 负责人:
- 金额:$ 6.75万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2003
- 资助国家:美国
- 起止时间:2003-09-05 至 2009-02-28
- 项目状态:已结题
- 来源:
- 关键词:BlindedChronic ProstatitisClinicalClinical InvestigatorClinical TrialsCollectionContractsData Coordinating CenterDiagnosticDiseaseEnrollmentJointsLong-Term EffectsManualsNational Institute of Diabetes and Digestive and Kidney DiseasesOperative Surgical ProceduresPatientsPharmaceutical PreparationsPlacebosProtocols documentationPrunus africanaRandomizedRecruitment ActivityResearchSabal serrulataSamplingScientistStandards of Weights and MeasuresSymptomsTherapy Clinical TrialsU-Series Cooperative Agreementschronic pelvic painlower urinary tract symptomsmembermenplacebo controlled studyprospectiveprostatitisresponse
项目摘要
This proposal is in response to an invitation for a cooperative agreement (contract) for one of ten clinical
centers to collaboratively establish, perform, maintain and evaluate multiple therapeutic trials, either
sequentially or concurrently for treatments of prostatitis through the collection and analysis of information
and clinical samples from patients with the disorder. The long-term objective will be attained by:
1. Developing a protocol(s) and manual of operations through the joint efforts of the Steering Committee
consisting of members of the clinical centers, data coordinating center, and the NIDDK project scientist. The
investigator from the clinical centers in conjunction with the data coordinating center, will have responsibility
in developing the protocol(s).
2. Recruiting and admitting patients into the study who have met agreed upon diagnostic entry criteria,
have standard demographic information, symptoms related to prostatitis and who will provide clinical
samples collected at established intervals will be enrolled.
Northwestern's proposed clinical trial is to conduct a prospective multi-center randomized blinded placebo
controlled trial of Saw palmetto (SP) or Pygeum africanum (PA) or placebo in patients with symptoms of
chronic pelvic pain syndrome (CPPS). Because of the widespread use of these medications for the
treatment of CPPS and lower urinary tract symptoms in men, and the neat total lack of well-performed
studies on the efficacy and long-term effects, a placebo controlled trial is needed as defined using the
CPCRN criterion.
本提案是对十个临床项目之一的合作协议(合同)邀请的回应。
中心合作建立,执行,维护和评估多种治疗试验,
用于前列腺炎的治疗
和临床样本。将通过以下方式实现长期目标:
1.通过指导委员会的共同努力,制定一项议定书和业务手册
由临床中心、数据协调中心和NIDDK项目科学家组成。的
临床中心的研究者与数据协调中心将负责
在制定议定书方面。
2.招募和接收符合商定诊断入选标准的患者进入研究,
有标准的人口统计信息,与前列腺炎有关的症状,谁将提供临床
将入组在确定的时间间隔采集的样本。
西北大学提出的临床试验是进行一项前瞻性多中心随机盲法安慰剂
锯棕榈(SP)或非洲臀果木(PA)或安慰剂在有以下症状的患者中的对照试验
慢性盆腔疼痛综合征(CPPS)。由于这些药物的广泛使用,
治疗CPPS和男性下尿路症状,且总缺乏整齐的表现
关于疗效和长期效应的研究,需要进行安慰剂对照试验,如使用
CPCRN标准。
项目成果
期刊论文数量(2)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Prostate secretions from men with chronic pelvic pain syndrome inhibit proinflammatory mediators.
- DOI:10.1016/j.juro.2010.05.086
- 发表时间:2010-10
- 期刊:
- 影响因子:0
- 作者:Thumbikat P;Shahrara S;Sobkoviak R;Done J;Pope RM;Schaeffer AJ
- 通讯作者:Schaeffer AJ
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ANTHONY J SCHAEFFER其他文献
ANTHONY J SCHAEFFER的其他文献
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{{ truncateString('ANTHONY J SCHAEFFER', 18)}}的其他基金
Role of CNS in Modulation of Pelvic Pain Syndrome
中枢神经系统在调节盆腔疼痛综合征中的作用
- 批准号:
7571839 - 财政年份:2008
- 资助金额:
$ 6.75万 - 项目类别:
Chronic Prostatitis Collaborative Research Network
慢性前列腺炎合作研究网络
- 批准号:
7036605 - 财政年份:2003
- 资助金额:
$ 6.75万 - 项目类别:
Chronic Prostatitis Collaborative Research Network
慢性前列腺炎合作研究网络
- 批准号:
7414183 - 财政年份:2003
- 资助金额:
$ 6.75万 - 项目类别:
Chronic Prostatitis Collaborative Research Network
慢性前列腺炎合作研究网络
- 批准号:
6873724 - 财政年份:2003
- 资助金额:
$ 6.75万 - 项目类别:
Chronic Prostatitis Collaborative Research Network
慢性前列腺炎合作研究网络
- 批准号:
6684671 - 财政年份:2003
- 资助金额:
$ 6.75万 - 项目类别:
Chronic Prostatitis Collaborative Research Network
慢性前列腺炎合作研究网络
- 批准号:
6947660 - 财政年份:2003
- 资助金额:
$ 6.75万 - 项目类别:
Chronic Prostatitis Collaborative Research Network
慢性前列腺炎合作研究网络
- 批准号:
7235697 - 财政年份:2003
- 资助金额:
$ 6.75万 - 项目类别:
Chronic Prostatitis Collaborative Research Network
慢性前列腺炎合作研究网络
- 批准号:
6798299 - 财政年份:2003
- 资助金额:
$ 6.75万 - 项目类别:
Chronic Prostatitis Collaborative Research Network
慢性前列腺炎合作研究网络
- 批准号:
7070391 - 财政年份:2003
- 资助金额:
$ 6.75万 - 项目类别:
Chronic Prostatitis Collaborative Research Network
慢性前列腺炎合作研究网络
- 批准号:
7259548 - 财政年份:2003
- 资助金额:
$ 6.75万 - 项目类别:
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