Core--Biostatistics and Data Management

核心--生物统计与数据管理

• 批准号: 7409145
• 负责人: Haesook T Kim
• 金额: $ 23.66万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7409145
• 关键词: Allogenic; Animal Experimentation; Biometry; Biostatistics Core; Cancer Center; Clinical; Clinical Data; Clinical Protocols; Clinical Research Protocols; Clinical Trials; Collaborations; Collection; Consultations; Dana-Farber Cancer Institute; Data; Data Analyses; Goals; Guidelines; Health Insurance Portability and Accountability Act; Hematopoietic Stem Cell Transplantation; Immune; Individual; Institution; Laboratories; Manuscripts; Medical; Mus; Patients; Process; Purpose; Quality Control; Range; Regulation; Research Infrastructure; Research Personnel; Research Project Grants; Research Subjects; Services; base; college; data acquisition; data management; design; member; programs; research study; sample collection; success

The goal of the research projects in this Program Project application is to elucidate the mechanisms of immune regulation following allogeneic hematopoietic stem cell transplantation (HSCT). Important to the success of this project is the biostatistical collaboration with individuals in each of the 3 projects and the 2 other Cores. The purpose of the Biostatistics and Data Management Core (Core B) is to provide the following services that will be utilized by all of the research projects included in this Program Project. Specific Aim 1: To provide biostatistical collaboration for clinical research protocols and laboratory and animal research studies. Specific Aim 2: To provide clinical data management for collection of individual patient information, data management support, forms design, and quality control for clinical protocols. Specific Aim 3: To provide a central mechanism for specimen collection, identification and tracking between the projects.

本计划项目的研究目标是阐明异基因造血干细胞移植（HSCT）后的免疫调节机制。该项目成功的重要因素是与3个项目和其他2个核心中的每个项目的个人进行生物统计合作。生物统计和数据管理核心（核心B）的目的是提供以下服务，供所有 研究项目包括在这个项目中。具体目标1：为临床研究方案和实验室及动物研究提供生物统计学合作。 具体目标二：为收集个体患者信息、数据管理支持、表格设计和临床方案质量控制提供临床数据管理。 具体目标3：为项目之间的标本收集、鉴定和跟踪提供一个中央机制。