Core--Biostatistics

本项目项目申请的研究目标是阐明GVHD的发病机制，并开发新的治疗方法来控制GVHD，同时维持GVL。对这个项目的成功至关重要的是与三个项目和其他核心的个人进行生物统计学合作。生物统计学核心的目的是提供以下服务，这些服务将被本计划项目中包括的所有研究项目所利用。为临床研究方案提供生物统计学合作。这包括临床方案的设计、实施、分析和报告的所有方面，以及数据处理和质量控制保证的指导。2. 为动物和实验室研究提供生物统计学合作。这包括这些研究的设计、实施、分析和报告的所有方面，包括实验室结果的协调

The goal of the research projects in this program project application is to elucidate the pathogenesis of GVHD and to develop new therapies designed to control GVHD while maintaining GVL. Important to the success of this project is the biostatistical collaboration with individuals in each of the 3 projects and the other Cores. The purpose of the Biostatistics Core is to provide the following services that will be utilized by all of the research projects included in this Program Project. 1. To provide biostatistical collaboration for clinical research protocols. This includes all aspects of design, conduct, analysis and reporting of the clinical protocols, and direction of data processing and quality control assurance. 2. To provide biostatistical collaboration for animal and laboratory research studies. This includes all aspects of design, conduct, analysis and reporting of such studies, including the coordination of laboratory results with parameters and outcomes from the clinical studies. 3. To supervise the data processing and data quality assurance, and to coordinate the efforts of the data coordinator and those of the data analyst in maintaining an accurate computerized database. 4. To provide computing resources for data processing, forms design, statistical analysis, standardized reporting, and quality control.