Core--Biostatistics

本项目申请的研究项目的目标是阐明GVHD的发病机制，并开发新的治疗方法，以控制GVHD，同时保持GVL。该项目成功的重要因素是与3个项目和其他核心中的个人进行生物统计合作。生物统计学核心的目的是提供以下服务，这些服务将被本计划项目中包含的所有研究项目所利用。 1.为临床研究方案提供生物统计协作。这包括临床方案的设计、实施、分析和报告的所有方面，以及数据处理和质量控制保证的方向。 2.为动物和实验室研究提供生物统计学合作。这包括此类研究的设计、实施、分析和报告的所有方面，包括实验室结果的协调 临床研究的参数和结果。 3.监督数据处理和数据质量保证，并协调数据协调员和数据分析员的工作，以保持准确的计算机化数据库。 4.为数据处理、表格设计、统计分析、标准化报告和质量控制提供计算资源。

The goal of the research projects in this program project application is to elucidate the pathogenesis of GVHD and to develop new therapies designed to control GVHD while maintaining GVL. Important to the success of this project is the biostatistical collaboration with individuals in each of the 3 projects and the other Cores. The purpose of the Biostatistics Core is to provide the following services that will be utilized by all of the research projects included in this Program Project. 1. To provide biostatistical collaboration for clinical research protocols. This includes all aspects of design, conduct, analysis and reporting of the clinical protocols, and direction of data processing and quality control assurance. 2. To provide biostatistical collaboration for animal and laboratory research studies. This includes all aspects of design, conduct, analysis and reporting of such studies, including the coordination of laboratory results with parameters and outcomes from the clinical studies. 3. To supervise the data processing and data quality assurance, and to coordinate the efforts of the data coordinator and those of the data analyst in maintaining an accurate computerized database. 4. To provide computing resources for data processing, forms design, statistical analysis, standardized reporting, and quality control.