Sleep-Wake Regulation and Emotion in Early Childhood

幼儿期的睡眠-觉醒调节和情绪

• 批准号: 7125423
• 负责人: MONIQUE K LEBOURGEOIS
• 金额: $ 14.27万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-23 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7125423
• 关键词: age difference; behavior test; behavioral /social science research tag; child psychology; circadian rhythms; clinical research; electroencephalography; emotions; homeostasis; human subject; longitudinal human study; melatonin; preschool child (1-5); sleep; sleep deprivation; wakefulness

DESCRIPTION (provided by applicant): This Mentored Research Scientist Award (K01) will enable the candidate to become an independent scientist focusing on maturational changes in bioregulatory sleep-wake processes and their relationship to the development of emotion regulation in early childhood (2-5 years). Career goals are to understand the role of sleep in emotion regulation and to apply basic bioregulatory processes research toward the development of interventions for the prevention of early sleep and emotional problems. Short-term research goals are to examine age-related differences in homeostatic and circadian processes and the effects of sleep (nap) restriction on emotion regulation in young children. The proposed 16-day cross-sectional home-based study with 2- and 5-year-olds (N=36) assesses (a) age-related differences in the accumulation of homeostatic sleep pressure (relationship between extended wakefulness and EEC slow-wave activity in naps taken after 4, 7, 10, 13, and 17 hours on five separate days), circadian phase (salivary melatonin onset), and phase angle (interval between circadian phase and wake time), and (b) the effects of nap restriction on emotion regulation (physiological and behavioral measures). The candidate will complete rigorous training with Mary Carskadon, Ph.D., an expert in sleep-wake regulation in young humans, and co-mentors with expertise in spectral analysis/mathematical modeling (Peter Achermann, Ph.D.) and emotion regulation (Ronald Seifer, Ph.D). Training goals are to develop a broader understanding of bioregulatory and developmental domains underlying sleep, circadian rhythms, and emotion; gain expertise in sleep-wake scoring, EEG spectral analysis, arid analysis of circadian rhythms data; acquire training in administering, coding, and analyzing data from emotion regulation measures; and increase understanding of longitudinal data analytic techniques. With this training, the candidate will be prepared for future longitudinal work on maturation changes in bioregulatory sleep-wake process in association with the development of emotion regulation.

描述（由申请人提供）：这一指导的研究科学家奖（K01）将使候选人成为一名独立的科学家，专注于生物调节睡眠效果过程的成熟变化及其与幼儿期（2-5岁）情绪调节的关系的关系。职业目标是了解睡眠在情绪调节中的作用，并将基本的生物调节过程研究应用于预防早期睡眠和情绪问题的干预措施的发展。短期研究目标是检查与年龄相关的稳态和昼夜节律过程的差异，以及睡眠（NAP）限制对幼儿情绪调节的影响。 The proposed 16-day cross-sectional home-based study with 2- and 5-year-olds (N=36) assesses (a) age-related differences in the accumulation of homeostatic sleep pressure (relationship between extended wakefulness and EEC slow-wave activity in naps taken after 4, 7, 10, 13, and 17 hours on five separate days), circadian phase (salivary melatonin onset), and phase angle (interval between circadian phase and wake time), and （b）NAP限制对情绪调节的影响（生理和行为度量）。候选人将与年轻人的睡眠效果调节专家玛丽·卡斯卡登（Mary Carskadon）以及具有光谱分析/数学建模专业知识的联合培训（Peter Achermann，Ph.D。）和情感调节（Ronald Seifer，Ph.D）。培训目标是对睡眠，昼夜节律和情感的生物调节和发展领域的更广泛理解；获得睡眠效果评分的专业知识，EEG光谱分析，昼夜节律数据的干旱分析；从情绪调节措施中获取管理，编码和分析数据的培训；并增加对纵向数据分析技术的理解。通过这项培训，将为候选人做好准备，以与情绪调节的发展有关的生物调节睡眠效果过程的成熟变化的纵向工作。