Psychological and Behavioral Impact of Cancer Screening

描述(申请人提供)：虽然癌症筛查可以降低死亡率和发病率，但参与癌症筛查可能会产生负面的心理和行为影响，即使没有发现恶性肿瘤。了解和管理癌症筛查的潜在负面影响是该奖项研究和指导活动的重点。PI花了20多年的时间进行行为肿瘤学研究，并指导博士后和博士后实习生。他的职业生涯专注于癌症检测、诊断、治疗和康复的心理、社会和行为层面。这一奖项将使他能够继续发展他的研究和指导活动。这项研究建立在Pl正在进行的关于经阴道(TVS)卵巢癌筛查的心理和行为结果的研究(R01 CA94036)和Pl最近关于良性乳腺活检(BBB)的心理和行为结果的研究的基础上。本文提出了三项协同性研究：(1)对异常电视视听筛查结果的心理和行为结果进行前瞻性、纵向研究；(2)开发和评估用于管理血脑屏障负面心理和行为影响的简明心理教育干预措施；(3)开发用于管理异常电视视听筛查结果负面影响的简短心理教育干预措施。指导计划建立在首席研究员作为私人投资的三个博士前和博士后研究培训补助金的先前经验的基础上。每年将为4-6名学员提供辅导。所有受训人员都参加了现有的行为肿瘤学研究培训计划。培训计划包括核心要素：(1)课程；(2)参与行为肿瘤学研究；(3)参与国家专业会议。这些核心要素使培训目标得以实现：(1)行为肿瘤学文献知识；(2)癌症医学基础知识；(3)参与研究的所有阶段；(4)获得对定量和定性研究至关重要的技能；(5)熟悉癌症检测、诊断和治疗发生的医疗环境；以及(6)专业发展。培训计划的总体目标是为受训人员在行为肿瘤学方面的独立调查人员的职业生涯做好准备。

DESCRIPTION (provided by applicant): While cancer screening can reduce mortality and morbidity, participation in cancer screening can have a negative psychological and behavioral impact, even when no malignancy is detected. Understanding and management of the potential negative impact of cancer screening is the focus of the research and mentoring activities for this award. The PI has spent over 20 years conducting research in behavioral oncology and mentoring pre- and postdoctoral trainees. His career has focused on the psychological, social, and behavioral dimensions of cancer detection, diagnosis, treatment, and recovery. This award will enable him to continue to develop his research and mentoring activities. The research builds on the Pl's ongoing study (R01 CA94036) of psychological and behavioral outcomes of transvaginal (TVS) screening for ovarian cancer and the Pl's recent study of psychological and behavioral outcomes of benign breast biopsy (BBB). Three synergistic studies are proposed: (1) prospective, longitudinal study of psychological and behavioral outcomes of an abnormal TVS screening result; (2) development and evaluation of brief psychoeducational interventions for managing the negative psychological and behavioral impact of BBB; and (3) development of brief psychoeducational interventions for managing the negative impact of an abnormal TVS screening result. The mentoring plan builds on the Principal Investigator's prior experience as PI for three pre-and postdoctoral research training grants. Mentoring will be provided for 4-6 trainees each year. All trainees participate in an existing research training program in behavioral oncology. The training program consists of core elements: (1) coursework; (2) participation in behavioral oncology research; and (3) participation in national professional meetings. These core elements enable achievement of training objectives: (1) knowledge of the behavioral oncology literature; (2) knowledge of the medical basis of cancer; (3) participation in all phases of research; (4) acquisition of skills critical to both quantitative and qualitative research; (5) familiarity with medical settings in which cancer detection, diagnosis, and treatment occurs; and (6) professional development. The overall goal of the training program is to prepare trainees for careers as independent investigators in behavioral oncology.