Research Priorities in Ambulatory Management of Obstructive Sleep Apnea Workshop

阻塞性睡眠呼吸暂停门诊管理研讨会的研究重点

• 批准号: 7413515
• 负责人: SAMUEL T. KUNA
• 金额: $ 4.65万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2008-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7413515
• 关键词: Research; Priorities; Ambulatory; Management; Obstructive

The application seeks partial financial support for a workshop on research priorities in the ambulatory management of obstructive sleep apnea (OSA) to be held on October 15-16, 2007 in Washington, DC. Moderate to severe OSA is estimated to affect 4% of adult females and 9% of adult males in the US and a large majority of these individuals are undiagnosed. A large body of data now supports that OSA is an independent risk factor for motor vehicle accidents, neurocognitive deficits, and cardiovascular morbidity and mortality. Substantial evidence also supports that appropriate treatment of OSA reduces the risk of these consequences. However there is a major problem with patient access to diagnosis and treatment of OSA based on the need to perform costly and labor-intensive polysomnography in a sleep laboratory. Technological improvements may allow for the use of simplified portable monitor testing for OSA in diverse settings, including unattended home recordings. Such an approach might reduce cost and increase patient access to testing, leading to earlier recognition of disease and faster initiation of treatment, thereby reducing the health care burden associated with OSA. Interest in the clinical application of portable monitor devices is growing rapidly, and in some contexts, portable monitoring has become a mainstay approach to the management of OSA. Despite the intuitive appeal of portable monitor testing, validation data remain limited. A recent report from the Institute of Medicine and evidence based reviews from AHRQ and professional societies find major deficiencies particularly with regard to unattended home portable monitor testing. The planned workshop on research priorities in ambulatory management of OSA is a direct response to these reports. The workshop will bring together diverse stakeholders with interest in portable monitor testing to establish the research priorities regarding portable monitor testing and develop specific recommendations regarding methodological issues in this critical area. We submit that this workshop is an essential ?next step? to ensuring that there is substantive advancement of scientific knowledge in this important field.

该申请为一个关于研究优先事项的研讨会寻求部分财政支持 阻塞性睡眠呼吸暂停 (OSA) 门诊治疗将于 2007 年 10 月 15 日至 16 日举行 在华盛顿特区。据估计，4% 的成年女性和 9% 的成年女性患有中度至重度 OSA 美国成年男性中的大多数人都没有得到诊断。一个大 现在的数据表明 OSA 是机动车事故的一个独立风险因素， 神经认知缺陷、心血管疾病发病率和死亡率。也有确凿的证据 支持 OSA 的适当治疗可以降低这些后果的风险。然而 患者获得 OSA 诊断和治疗的一个主要问题是 需要在睡眠实验室进行昂贵且劳动密集型的多导睡眠图检查。 技术改进可能允许使用简化的便携式监视器测试 OSA 在不同的环境中，包括无人值守的家庭录音。这种方法可能会 降低成本并增加患者接受检测的机会，从而更早地识别疾病并 更快地开始治疗，从而减轻与 OSA 相关的医疗保健负担。 人们对便携式监测设备临床应用的兴趣正在迅速增长，并且在某些领域 在这种背景下，便携式监测已成为 OSA 管理的主要方法。 尽管便携式显示器测试具有直观的吸引力，但验证数据仍然有限。最近的一个 医学研究所的报告以及 AHRQ 和专业人士的基于证据的审查 社会发现重大缺陷，特别是在无人值守的家用便携式监视器方面 测试。计划举办的关于 OSA 门诊管理研究优先事项的研讨会是 对这些报告的直接回应。该研讨会将汇集不同的利益相关者 对便携式显示器测试的兴趣，以确定便携式显示器的研究重点 测试并制定有关这一关键方法论问题的具体建议 区域。我们认为本次研讨会是重要的“下一步”？以确保有 这一重要领域的科学知识取得了实质性进展。