SLEEP & FRONTAL LOBE FUNCTION IN REHAB FROM STROKE & TRAUMATIC BRAIN INJURY

由于创伤或其他原因造成的脑损伤后，睡眠障碍可能会很严重 中风，但对其流行率和后果知之甚少。 患者经常抱怨睡眠障碍和睡眠不足的症状。 做梦，并表现出注意力不集中，记忆困难，容易 疲劳性，通常与睡眠障碍有关 没有受伤的人群。在该协议中，代表的睡眠 脑损伤和中风患者的样本将被准确地描述，并且 与大脑功能的独立观察相关的发现如下 通过正式的神经心理评估来描述。主题将是 在参加急症后康复计划时进行评估 德克萨斯州加尔维斯顿的过渡学习社区。结果将会是 增加我们对大脑-行为关系的理解，并提供 对这些人群进行有益干预的科学依据 更好的行为和药物治疗。这种干预可以 直接改善这些患者的生活质量，使他们能够 更好地参与其他康复工作。因为斯托克和创伤 是美国大脑损伤的主要原因，并造成相当大的 残疾以及保健和康复的支出， 这些结果可能会对公共卫生产生重大影响。

Sleep disturbance can be significant after brain damage due to trauma or stroke, but little is known regarding its prevalence and consequences. Patients often complain of symptoms of disturbed sleep and lack of dreaming, and demonstrate inattentiveness, memory difficulties, and easy fatigability, which are commonly associated with sleep disturbance in uninjured populations. In this protocol the sleep of a representative sample of TBI and stroke patients will be precisely characterized, and the findings correlated with independent observations of brain function as delineated through formal neuropsychological evaluation. Subjects will be evaluated while attending the post-acute rehabilitation program of the Transitional Learning Community in Galveston, Texas. The results will increase our understanding of brain-behavior relationships, and provide a scientific basis for intervening beneficially in these populations with better behavioral and pharmacological therapies. Such interventions may directly improve quality of life in these patients and enable them to better engage in other rehabilitation efforts. Because storke and trauma are leading causes of brain damage in the U.S., and cause considerable disability as well as expenditure for health care and rehabilitation, these results could have major public health impact.