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中文摘要
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描述(由申请人提供):本次研讨会计划作为第二届国际神经性疼痛大会的卫星会议,2007年6月7日至10日,德国柏林。Rolf-Detlef Treede博士是大会的副主席,也是本次研讨会的联合主席。本次研讨会的重点是热痛觉-在其神经生物学和翻译潜力方面。我们计划讨论和探讨热痛觉分子和细胞生物学的最新进展,并将这些信息与成像技术(FMRI, MEG, EEG)的最新进展联系起来。本次研讨会的主要目标是:1)以相关神经生物学为基础,在临床研究中开发热伤害性方案的应用;2)发展工业界和学术界之间的合作,以促进该领域的转化研究。从来没有一个研讨会旨在开发一种方法,用于选择性激活不同种群的伤害感受器,包括潜在的生理学和分子靶标(例如,瞬时受体电位家族),并将其与临床有用的最新神经成像技术联系起来。这个国际论坛面向基础科学家、医生、心理学家(多达120名参与者)和其他对人类疼痛和镇痛研究感兴趣的卫生专业人员。重点将是利用当前最先进的刺激方法(激光,辐射和接触热装置)和记录(心理物理学,诱发皮层电位,功能性磁共振成像,脑磁图)进行疼痛研究和诊断,以及临床镇痛药的开发。
英文摘要
DESCRIPTION (provided by applicant): This workshop is planned as a satellite meeting of Second International Congress on Neuropathic Pain, June 7 - 10, 2007, Berlin, Germany. Dr. Dr. Rolf-Detlef Treede, who is vice chair of the congress, is co- chair of the proposed workshop. This workshop is focused on thermal nociception - both in terms of its neurobiology and its translational potential. We plan to discuss and explore the latest advances in molecular and cell biology of thermal nociception, and link this information to state of art of imaging (FMRI, MEG, EEG). The major goals of this workshop are to: 1) develop the application of thermal nociceptive protocols for clinical research with grounding in relevant neurobiology and 2) develop collaboration between Industry and academia to foster translational research in this area. There has never been a workshop aimed at developing a methodology for selective activation of different populations of nociceptors encompassing both the underlying physiology and molecular targets (e.g., the transient receptor potential family), and relating it to clinically useful state-of-the art neuroimaging techniques. This international forum is for basic scientists, physicians, psychologists (up to 120 participants), and other health professionals interested in state-of-the-art human pain and analgesia research. The focus will be on the utilization of current state-of-the-art methodologies of stimulation (lasers, radiant and contact heat devices) and recording (psychophysics, evoked cortical potentials, functional magnetic resonance imaging, magnetoencephalography) for pain research and diagnosis, and for clinical analgesic development.
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Discovery and Validation of a Novel Response Biomarker Signature for Painful Peripheral Neuropathy
  • 批准号:
    10677537
  • 项目类别:
  • 资助金额:
    $50.27万
  • 财政年份:
    2022
  • 负责人:
    Mikhail I. Nemenov
  • 依托单位:
Discovery and Validation of a Novel Response Biomarker Signature for Painful Peripheral Neuropathy
  • 批准号:
    10357531
  • 项目类别:
  • 资助金额:
    $100.02万
  • 财政年份:
    2022
  • 负责人:
    Mikhail I. Nemenov
  • 依托单位:
Oro-facial non Contact Thermal Stimulator
  • 批准号:
    7160634
  • 项目类别:
  • 资助金额:
    $11.48万
  • 财政年份:
    2006
  • 负责人:
    Mikhail I. Nemenov
  • 依托单位:
Selective Laser Stimulator of C and A delta fibers
  • 批准号:
    7197863
  • 项目类别:
  • 资助金额:
    $2.34万
  • 财政年份:
    2004
  • 负责人:
    Mikhail I. Nemenov
  • 依托单位:
海外基金