Behavior Intervention on Anxiety in Children with Autism

自闭症儿童焦虑的行为干预

• 批准号: 7232076
• 负责人: Amy Drahota
• 金额: $ 2.99万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7232076
• 关键词: Address; Aftercare; Age; Anxiety; Anxiety Disorders; Autistic Disorder; Behavior Therapy; Child; Clinic; Clinical; Cognitive Therapy; Comorbidity; Condition; Control Groups; Daily; Diagnosis; Experimental Designs; Failure; Fellowship; Heterogeneity; High Prevalence; Impairment; Individual; Intervention; Lead; Life; Literature; Manuals; Measures; Modification; Names; Outcome; Parents; Phase; Psychopharmacology; Randomized; Range; Rate; Research Personnel; Risk; Schools; Self Efficacy; Social Adjustment; Social Functioning; Subgroup; Symptoms; Testing; Voluntary Mutism; Waiting Lists; autism spectrum disorder; daily functioning; design; experience; functional disability; improved; programs; psychosocial; remediation; size; skills; social; social skills; success

DESCRIPTION (provided by applicant): Children with high functioning autism (HFA) are at heightened risk for anxiety disorders when compared with neurotypical children. The high prevalence rate of anxiety disorders in HFA is suggestive of a distinct subgroup of children on the autism spectrum-an "anxious-inhibited" subgroup. Due to complications that comorbid diagnoses can add to the adaptive functioning of children with HFA, and because the psychosocial intervention literature has been marked with few successes, researchers have recommended addressing specific symptoms and prevalent subgroups found among children with HFA. The proposed study is designed to examine the efficacy of a recently modified cognitive behavioral therapy (CBT) program in the remediation of anxiety symptoms in children with HFA. This study will include a pilot phase with 3 children with HFA ranging in age from 7-13 years, allowing further refinement and modification of the CBT manual. Thereafter, 28 children will be randomly assigned to either immediate treatment or waitlist control conditions; children and primary parents will be provided a multimodal CBT intervention in a clinic setting. Children assigned to the waitlist control group will receive the full treatment after 3 months. This experimental design will allow me to test the impact of CBT on children's anxiety and adaptive functioning. Measures of anxiety, social, academic, and daily living skills functioning, as well as treatment acceptability will serve as primary outcomes and will be assessed immediately following intervention and at 3 months post treatment.

描述（由申请人提供）：与神经典型儿童相比，患有高功能自闭症（HFA）的儿童患焦虑症的风险增加。 HFA中焦虑症的高患病率暗示着自闭症谱系上的一个独特的儿童亚组 - “焦虑抑制”亚组。由于合并诊断的并发症可能会增加HFA儿童的适应性功能，并且由于心理社会干预文献的标志性很少，因此研究人员建议解决HFA儿童中发现的特定症状和普遍的亚组。拟议的研究旨在检查最近修改的认知行为疗法（CBT）计划在HFA儿童焦虑症状中的疗效。这项研究将包括一个试点阶段，其中3名HFA儿童的年龄从7-13岁不等，可以进一步改进和修改CBT手册。此后，将有28名儿童随机分配给立即治疗或候补控制条件；在诊所环境中，将为孩子和主要父母提供多模式的CBT干预。分配给候补名单对照组的孩子将在3个月后获得完整的治疗。这种实验设计将使我能够测试CBT对儿童焦虑和适应性功能的影响。焦虑，社会，学术和日常生活技能以及治疗可接受性的度量将作为主要结果，并在干预后和治疗后3个月后立即评估。