SEVERE CHRONIC NEUTROPENIA - TISSUE REPOSITORY

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 本研究的目的是通过对患有这种疾病的人及其直系亲属的血液，骨髓和其他细胞的研究，了解更多关于严重慢性中性粒细胞减少症的原因。 这项研究比较了严重慢性中性粒细胞减少症患者的血液和骨髓样本，并与他们的直系亲属或正常志愿者的样本进行了对比。 该研究正在研究重度慢性中性粒细胞减少症的遗传原因，并比较中性粒细胞减少症受试者与非中性粒细胞减少症受试者的结果。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of this study is to learn more about the causes of severe chronic neutropenia through the study of blood, bone marrow, and other cells of people with this condition, and their immediate relatives. The study compares the blood and bone marrow samples of people with severe chronic neutropenia in contrast to the samples of their immediate relatives or normal volunteers. The study is looking at the genetic causes for severe chronic neutropenia and comparing the results of the subjects with neutropenia to the subjects without neutropenia.