NIH Biotechnologist: Authentic Exploration of Biotechnology in Health Science

NIH 生物技术专家：健康科学中生物技术的真实探索

• 批准号: 7219820
• 负责人: STEVEN Douglas MOORE
• 金额: $ 10万
• 依托单位: SCIENCE-APPROACH
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-15 至 2009-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7219820
• 关键词: Accounting; Agriculture; Basic Science; Biological; Biotechnology; Data; Data Analyses; Development; Diagnosis; Diagnostic; Education; Educational process of instructing; Endowment; Ethics; Feedback; Food; Forensic Medicine; Foundations; Funding; Genetic; Genetic Research; Genomics; Goals; Grant; Health Sciences; Institution; Instruction; Knowledge; Laboratories; Learning; Living Standards; Maps; Marketing; Medical; Methodology; Mission; Modeling; National Institute of Mental Health; Numbers; Other Genetics; Pharmaceutical Preparations; Pharmacologic Substance; Phase; Plasmids; Play; Problem Solving; Regenerative Medicine; Research; Restriction Mapping; Rewards; Rights; Role; Science; Science of genetics; Scientist; Small Business Funding Mechanisms; Small Business Innovation Research Grant; Standards of Weights and Measures; Students; Support of Research; Techniques; Technology; Testing; Therapeutic; United States; United States National Institutes of Health; Update; Vaccines; Work; college; design; experience; high school; image processing; improved; innovation; instructor; interest; literate; member; programs; prototype; research study; software development; teacher; tool; usability

DESCRIPTION (provided by applicant): The proposed NIH Biotechnologist: Authentic Explorations of Biotechnology, Genetics, and Genomics in Health Science project will produce a model lesson-"Restriction Mapping: Mapping restriction sites on a plasmid"-derived from the Biotechnologist instructional materials developed by the nonprofit Center for Image Processing in Education. Designed to be a supplementary activity for high school and college instruction, the lesson will be restructured using the Understanding by Design methodology of Wiggins and McTighe (2005); updated with current content material relevant to the mission of the National Institutes of Health (NIH); enhanced with technologies that promote customizability by instructors and interactivity for learners; and packaged in an eLearning format to facilitate testing and improve its usability for instructors and students. The lesson will introduce the learner to restriction mapping in an engaging manner, provide online tools that allow the learner to explore the topic by conducting a basic science experiment, analyze data gathered during the experiment, reflect on what they have learned, and integrate their discoveries with narrative accounts of the discovery of similar knowledge. The lesson will serve as a prototype for a full set of materials to be developed with funding from a Phase II SBIR grant. Updating, improvement, and repurposing of Biotechnologist will be conducted by Science Approach, a for-profit corporation. The project will accomplish the following milestones: (1) develop a model NIH Biotechnologist lesson by updating, improving, and repurposing the existing "Restriction Mapping: Mapping restriction sites on a plasmid" lesson from Biotechnologist; (2) pilot test the model lesson with a panel of high school teachers, college instructors, and undergraduate students to uncover usability issues, identify barriers to successful implementation of the materials, and receive feedback about the model lesson and planned set of materials; (3) analyze the pilot test data and revise the model lesson into a template for the full set of instructional materials to be produced in Phase II; (4) finalize a table of contents for the full set of NIH Biotechnologist materials; (5) Evaluate channels for collaborative development, marketing, and distribution of NIH Biotechnologist by exploring a relationship with the National Science Teachers Association; and (6) create a plan for developing and field-testing the full set of instructional materials during a Phase II SBIR project. By immersing students in real research data from NIH-supported research, the NIH Biotechnologist project will (1) help promote development of a scientifically literate public that can carry forward the endowment of science and technology that has provided the United States with its high standard of living and (2) introduce learners to the key role that NIH-supported research in biotechnology, genetics, and genomics plays in improving biomedical diagnoses, treatments, and research. The proposed NIH Biotechnologist: Authentic Explorations of Biotechnology, Genetics, and Genomics in Health Science project will involve high school and undergraduate students in learning about biotechnology, genetics, and genomics. Not only will the proposed instructional materials highlight the key role that NIH-supported research plays in improving biomedical diagnoses, treatments, and research, NIH Biotechnologist will promote development of a scientifically literate public that can carry forward the endowment of science and technology that has made the United States a leader in the field of biomedicine and provided its citizens with the high standard of living the nation enjoys.

描述（由申请人提供）：拟议的NIH生物技术专家：健康科学项目中生物技术，遗传学和基因组学的真实探索将产生一个示范课-“限制性图谱：质粒上的限制性位点图谱”-来自非营利中心开发的生物技术专家教学材料图像处理教育。该课程旨在作为高中和大学教学的补充活动，将采用Wiggins和McTighe（2005年）的“通过设计理解”方法对课程进行调整;更新与美国国立卫生研究院（NIH）使命相关的现有内容材料;采用促进教员可定制性和学习者互动性的技术予以加强;并以电子学习格式打包，以方便测试并提高教师和学生的可用性。该课程将以引人入胜的方式向学习者介绍限制映射，提供在线工具，允许学习者通过进行基础科学实验来探索主题，分析实验期间收集的数据，反思他们学到的东西，并将他们的发现与发现类似知识的叙述性帐户相结合。该课程将作为一套完整材料的原型，这些材料将由第二阶段SBIR赠款提供资金。生物技术专家的更新、改进和再利用将由营利性公司科学方法进行。该项目将完成以下里程碑：（1）通过更新、改进和重新利用现有的“限制性图谱：质粒上的限制性位点图谱”课程，开发一个NIH生物技术专家课程模型;（2）由高中教师、大学教师和本科生组成的小组对示范课进行试点测试，以发现可用性问题，找出成功实施教材的障碍，并听取有关示范课和计划教材的反馈意见;（3）分析试点测试数据，并将示范课修订为第二阶段编制的全套教材的模板;（4）最终确定NIH生物技术专家全套教材的目录;（5）通过探索与国家科学教师协会的关系，评估合作开发、营销和分发NIH生物技术专家的渠道;（6）在第二阶段SBIR项目期间制定开发和现场测试全套教学材料的计划。通过让学生沉浸在来自NIH支持的研究的真实的研究数据中，NIH生物技术专家项目将（1）有助于促进科学素养的公众的发展，从而能够发扬为美国提供高生活水平的科学和技术的天赋，（2）向学习者介绍NIH支持的生物技术，遗传学，基因组学在改善生物医学诊断、治疗和研究方面发挥着重要作用。拟议的NIH生物技术专家：健康科学项目中的生物技术，遗传学和基因组学的真实探索将涉及高中和本科生学习生物技术，遗传学和基因组学。不仅将拟议的教学材料突出了NIH支持的研究在改善生物医学诊断，治疗和研究中发挥的关键作用，NIH生物技术专家将促进科学素养的公众的发展，可以发扬科学和技术的禀赋，使美国成为生物医学领域的领导者，并为其公民提供国家享有的高标准生活。