MIDARP at CCNY

CCNY 的 MIDARP

• 批准号: 7234457
• 负责人: EITAN FRIEDMAN
• 金额: $ 42.39万
• 依托单位: CITY COLLEGE OF NEW YORK
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-01 至 2010-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7234457
• 关键词: American; Area; Biochemistry; Biological; Biological Sciences; Biology; Biomedical Engineering; Biophysics; Brain Diseases; CCL7 gene; Career Choice; Cell Nucleus; Chemistry; Cities; Classification; Cocaine; Collaborations; Commit; Core Facility; Dedications; Development; Dopamine D1 Receptor; Drug abuse; Education; Educational workshop; Environment; Exposure to; Extramural Activities; Faculty; Financial Support; Fostering; Functional disorder; Funding; Future; Goals; Immigrant; Individual; Institution; Investigation; Laboratories; Leadership; Location; MAP Kinase Gene; Measures; Mentors; Minority; Mission; Molecular; Molecular Biology; N-Methyl-D-Aspartate Receptors; National Institute of Drug Abuse; Neurobiology; Neurons; New York; Numbers; Operative Surgical Procedures; Participant; Perinatal Exposure; Pharmacology; Physiology; Population; Positioning Attribute; Productivity; Program Evaluation; Psychology; Recording of previous events; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Resources; Schools; Science; Scientist; Score; Secure; Social Sciences; Solid; Structure; Students; Support of Research; Training; Training Programs; Training Support; Transcend; Underrepresented Minority; United States National Institutes of Health; Universities; addiction; base; career; college; design; desire; drug of abuse; experience; improved; in utero; interest; medical schools; neurochemistry; prenatal; programs; research and development; science education; social; structural biology; success; symposium

DESCRIPTION (provided by applicant): CCNY, the science flagship of the CUNY is heavily (75%) involved in educating students from underrepresented minority populations. It is our goal to develop a program at CCNY that draws on existing strengths and focuses and promotes investigations on drug abuse. Our clear aim is to encourage entry of young minority undergraduates and graduate scholars to a career in drug abuse research. The program is thematically focused on the long-term sequel of in utero exposure to cocaine. The neurobiological investigations encompass research on molecular, cellular, and neurochemical effects of exposure to cocaine. The program includes active research faculty, educators specializing in drug abuse graduate and undergraduate research students who share interest in the neurobiology of stimulants and in understanding addiction as a brain disease. The aims of the application are to enhance the breadth of research at CCNY that focuses on the neurobiology of drugs of abuse. The program is also designed to develop individual research projects and to stimulate interest of other faculty and students in research on drug abuse. The overall aim of this program is to facilitate the career development of minority undergraduate and graduate students who will mature into independent investigators of the future. The specific projects proposed are: 1. MAPK in in utero cocaine-induced abnormal neuron differentiation. 2. GSK3beta in prenatal cocaine-induced D1 dopamine receptor dysfunction and dendritic elongation. 3. Prenatal cocaine alterations of NMDA receptor assembly. 4. Protection against the glutametergic effects of in utero cocaine. The PI is an established drug abuse researcher with over 30 years experience. He and other senior faculty will serve as mentors to junior scientists. As a group the faculty are extremely experienced in attracting and mentoring young minority scholars to research. The Institution has committed significant financial support to help secure the success of this program that aims to enhance interest in minorities in the choice of career in drug abuse research.

描述（由申请人提供）： CCNY，CUNY的科学旗舰店大量（75％）参与教育来自代表性不足的少数群体的学生。我们的目标是在CCNY开发一项计划，该计划借鉴了现有的优势，重点并促进对药物滥用的调查。我们的明确目的是鼓励年轻的少数族裔大学生和研究生学者从事药物滥用研究的职业。该程序主题关注子宫内对可卡因的长期续集。神经生物学研究涵盖了暴露于可卡因的分子，细胞和神经化学作用的研究。该计划包括积极的研究教师，专门从事药物滥用研究生的教育工作者以及对兴趣兴趣的兴趣兴趣的兴趣以及将成瘾视为脑部疾病的兴趣。该应用程序的目的是增强CCNY的研究广度，该研究的重点是滥用药物的神经生物学。该计划还旨在开发单个研究项目，并激发其他教职员工和学生对药物滥用研究的兴趣。该计划的总体目的是促进少数本科生和研究生的职业发展，他们将成为未来的独立调查员。提出的特定项目是：1。MAPKIN子宫可卡因诱导的异常神经元分化。 2。产前可卡因诱导的D1多巴胺受体功能障碍和树突延伸的GSK3Beta。 3。NMDA受体组件的产前可卡因改变。 4。防止子宫可卡因的谷氨酸效应。 PI是一名拥有30多年经验的著名药物滥用研究人员。他和其他高级教师将担任初级科学家的导师。作为一个小组，该教师在吸引和指导少数民族学者研究方面非常有经验。该机构已提供了大量的财政支持，以帮助确保该计划的成功，旨在增强对少数民族在药物滥用研究中的职业选择的兴趣。