Drew MIDARP（药物滥用研究基础设施）-猫眼课题宝

Drew MIDARP（药物滥用研究基础设施）

批准号：

7494900

负责人：

THEODORE C FRIEDMAN

金额：

$6.16万

依托单位：

CHARLES R. DREW UNIVERSITY OF MED & SCI

依托单位国家：

美国

项目类别：

财政年份：

2004

资助国家：

美国

项目状态：

已结题

起止时间：

2004-09-15 至 2008-04-30

来源：

https://reporter.nih.gov/project-details/7494900

关键词：

AIDS education/prevention Abscess Absence of pain sensation Acetylcholinesterase Achievement Acquired Immunodeficiency Syndrome Acute Address Administrator Adolescent Adrenal Gland Hyperfunction Adrenal Glands Adult Adverse effects Advisory Committees Affect Affinity African African American Agreement Air Alcohol dependence Alcohol or Other Drugs use Alcoholism Alcohols Aldosterone Am 80 American American Heart Association Americas Anabolism Analgesics Androgens Angiotensin Type 1a Receptor Animals Annual Reports Antigens Apoptosis Appendix Applications Grants Appointment Area Argipressin Arts Aspartic Endopeptidases Attenuated Autistic Disorder Autoimmune Process Award Awareness Basic Science Bathing Beds Behavior Behavioral Assay Berlin Bilateral Biliary calculi Binding Binding Sites Biochemical Biochemistry Biological Biological Assay Biological Sciences Biology Biomedical Research Biometry Bisexual Blood Blood - brain barrier anatomy Blood Vessels Body Composition Body Temperature Bone Marrow Book Chapters Boron Bos taurus Boxing Brain Brain Diseases Brain region Breast Breeding Budgets CD4 Positive T Lymphocytes CRH gene Calcium California Cancer Center Support Grant Carbohydrates Carbon Dioxide Cardiovascular system Caring Case Study Catchment Area Categories Cattle Cell Death Cell Line Cell physiology Cells Cellulitis Centers of Research Excellence Central obesity Cerebral cortex Cerebrovascular Circulation Chairperson Characteristics Chemical Agents Chemical Exposure Chemicals Chemistry Chemosensitization Child Cholelithiasis Chromatography Chronic Chronic Fatigue Syndrome Chronic Kidney Failure Circadian Rhythms Cities Class Client Clinic Clinical Clinical Endocrinology Clinical Research Cocaine Cocaine Dependence Cognitive Therapy Cohort Studies Collaborations Colon Carcinoma Color Commit Committee Members Communicable Diseases Communication Communities Community Health Community Health Education Community Participation Community Surveys Comorbidity Compassion Complement Complex Computer Systems Computers Condition Congestive Heart Failure Consultations Contracts Core Facility Corticosterone Corticotropin Corticotropin-Releasing Hormone Country County Crack Cocaine Cushing Syndrome Cyclic AMP DNA DNA analysis Daily Data Delta Sleep-Inducing Peptide Dependence Depth Detergents Development Development Plans Dextroamphetamine Diabetes Insipidus Diabetes Mellitus Direct Costs Discipline of Nursing Disease Disruption Disulfiram Doctor of Medicine Doctor of Philosophy Dopamine Dose Double-Blind Method Drug Addiction Drug Receptors Drug Rehabilitation Centers Drug abuse Drug usage Drug user Dynorphins Economic Burden Economics Education Educational Activities Educational Curriculum Educational process of instructing Effectiveness Electronics Elements Employee Employment End stage renal failure Endocrine Endocrine System Diseases Endocrine system Endocrinologist Endocrinology Endometrium Endopeptidases Endorphins Enkephalins Enrollment Ensure Environment Environmental Risk Factor Enzymes Epidemiologic Methods Epidermal Growth Factor Receptor Equilibrium Equipment Equipment and supply inventories Evaluation Evidence based practice Excision Exercise Exposure to Face Facilities and Administrative Costs Facility Construction Funding Category Factor Analysis Faculty Family Fatigue Fatty acid glycerol esters Federal Government Fee-for-Service Plans Fees Fellowship Fellowship Program Female Financial compensation Floor Formalin Tests Fostering Foundations Friction Friends Fringe Benefit Functional disorder Funding Funding Mechanisms Future Gays Gel Gene Deletion Gene Expression Gene Proteins Generations Genes Genetic Genetic Markers Genetic Polymorphism Genotype Gills Glucocorticoids Gly-Lys-Arg-oxytocin Glycine Goals Golgi Apparatus Gonadal Steroid Hormones Grant Gray unit of radiation dose Growth Growth Factor HIV HIV Infections HIV Seroprevalence HIV-1 HPSE gene Harm Reduction Hazardous Substances Head Health Hearing Hemodialysis Hepatitis Hepatitis C High Pressure Liquid Chromatography High Prevalence Hispanic Americans Hispanics Histology Homeostasis Hormonal Hormones Hospitals Hour House Staffs Housing Human Human Resources Hydrolase Hyperaldosteronism Hyperplasia Hypertension Hypopituitarism Hypothalamic structure Hypoxia IACUC Ice Illicit Drugs Image Immunohistochemistry In Situ Hybridization In Vitro Incubators Individual Induction of Apoptosis Inferior Informal Social Control Information Technology Infrastructure Activities Inherited Injecting drug user Injection of therapeutic agent Inpatients Institution Instruction Internal Medicine International Internet Intramural Research Training Award Ions Italy Journals Keloid Kidney Kidney Diseases Kinetics Knock-out Knockout Mice Knowledge Label Laboratories Laboratory Animals Laboratory Assistant Laboratory Research Latino Laws Lead Learning Leptin Letters Life Lipodystrophy Liquid substance Liver Living Costs Lobe Location Los Angeles Malignant Neoplasms Manuscripts Marshal Mass Spectrum Analysis Master of Business Administration Master of Public Health Measures Mediating Medical Medical Education Medical Staff Medical Students Medical center Medicine Meditation Membrane Mental Depression Mental Health Services Mental disorders Mentors Mentorship Messenger RNA Metabolic Metabolic Syndrome X Metabolism Methionine Enkephalin Methods Michigan Microscope Microtome - medical device Minority Minority Groups Mismatch Repair Mission Modeling Modification Molecular Molecular Biology Molecular Genetics Molecular Medicine Molecular Virology Monitor Mono-S Monograph Morphine Morphine Receptors Mosses Motor Mucous Membrane Multi-Institutional Clinical Trial Multicenter Studies Municipalities Mus Mutate Mutation N-Methyl-D-Aspartate Receptors N-benzyloxycarbonylprolylprolinal NIH Program Announcements Naloxone Naltrexone Names Narcotic Antagonists Narcotics National Center for Research Resources National Institute of Child Health and Human Development National Institute of Diabetes and Digestive and Kidney Diseases National Institute of Drug Abuse National Institute on Alcohol Abuse and Alcoholism National Research Council Nature Necrosis Needle-Exchange Programs Needles Needs Assessment Neighborhoods Nerve Degeneration Neuroblastoma Neurons Neuropeptides Neurosciences Neurosecretion Neurosecretory Systems New York Nicotine Nitrogen Nociception Non-Insulin-Dependent Diabetes Mellitus Nucleic Acids Nucleus Accumbens Numbers Nurses Nursing Faculty Obesity Occupational Exposure Ohio Operative Surgical Procedures Opiate Addiction Opiates Opioid Opioid Peptide Opioid Receptor Opioid Receptor Binding Oral Oral cavity Orthostasis Orthostatic Hypotension Outcome Ovary Overdose Overweight Oxytocin PC12 Cells PPAR gamma Pain Pain Research Pamphlets Pancreas Paper Paraffin Embedding Paroxetine Participant Particulate Pathway interactions Patient Care Patient Discharge Patients Pattern Pediatrics Peer Review Peptide Hydrolases Peptides Personal Satisfaction Persons Pertussis Toxin Petrosal Sinus Sampling Pharmaceutical Preparations Pharmacologic Substance Pharmacology Pharmacology and Toxicology Phase Photocopying Physical Function Physician Assistants Physicians Physiological Physiology Pilot Projects Pituitary Gland Placebos Placental Choriocarcinoma Play Policies Polymerase Chain Reaction Population Positioning Attribute Postdoctoral Fellow Power Sources Preparation Prevalence Prevention Prevention education Price Principal Investigator Prize Pro-Opiomelanocortin Process Production Productivity Professional Education Program Evaluation Progress Reports Prohormone Convertase Property Proprotein Convertase 1 Proprotein Convertase 2 Protease Inhibitor Protein Kinase C Protein Microchips Proteins Proteomics Protocols documentation Provider Psychiatry Psychopharmacology Public Health Publications Published Comment Publishing Purpose Questionnaires REM Sleep Radioimmunoassay Radiology Specialty Railroads Range Rate Rattus Readiness Receptor Signaling Receptor Up-Regulation Recombinants Recommendation Recruitment Activity Registered nurse Regulation Rehabilitation Centers Relative (related person)Renin Reporting Request for Proposals Research Research Activity Research Ethics Committees Research Infrastructure Research Institute Research Methodology Research Personnel Research Project Grants Research Support Residencies Resources Rewards Rhode Island Risk Risk Behaviors Risk Factors Risk Reduction Rodent Role Rotation Safety Sampling San Francisco Schedule Schools Science Scientist Scintillation Counter Score Secretory Vesicles Seeds Series Serine Protease Serine carboxypeptidase Serotonin Serum Services Sexual Transmission Signal Transduction Sinus Site Sleep Slow-Wave Sleep Social Behavior Societies Sorting - Cell Movement Source Specific qualifier value Speed Spinal Spottings Staff Development Staging Standards of Weights and Measures Stress Structure Students Study Section Substance P Substance abuse problem Supervision Support of Research Surveys Switzerland Syndrome Syringes System Systems Analysis TNFRSF5 gene Tablets Taurine Techniques Technology Teleconferences Testing Testosterone Therapeutic community technique Thyroid Gland Thyroid Hormone Receptor Thyroid Hormones Thyrotropin-Releasing Hormone Time Tissue Sample Tissues Title Tort Toxic effect Training Training Programs Training and Education Training and Infrastructure Transcriptional Activation Transgenic Mice Transgenic Mouse Facility Translational Research Translations Travel Treatment Protocols Trust U-Series Cooperative Agreements USA Georgia United States Health Resources and Services Administration United States National Institutes of Health Universities University Hospitals Up-Regulation Vascular Endothelial Growth Factors Vasopressins Vesicle Veterinarians Viagra Visceral Visit Visual Wages War Water Week Weight Western Asia Georgia Western Blotting Wild Type Mouse Withdrawal Woman Wood material Work Writing X-Ray Film Yeasts Youth abstracting addiction alcohol abuse therapy alcohol and other drug alcohol research animal care autistic children base bean behavior influence biobehavior biomedical scientist brain research brush border membrane carboxypeptidase H cardiovascular risk factor career clinically relevant cohort college comparative cost cytokine cytotoxic cytotoxicity data management day delta opioid receptor design diabetic rat digital disorder prevention disorder risk dissemination research drug abuser drug of abuse drug rehabilitation endogenous opioids experience follow-up foot functional status fundamental research gene therapy germ free condition glucagon-like peptide 1 health disparity high risk sexual behavior high school human prostaglandin D2 receptor human subject hypothalamic-pituitary-adrenal axis immunocytochemistry improved in vivo inhibitor/antagonist inner city insight insulin sensitivity interest lecturer lectures link protein lipid metabolism male malignant mouth neoplasm medical schools member men meter molecular oncology multicatalytic endopeptidase complex muscle metabolism mutant neural circuit neurochemistry nociceptin novel older men peptide hormone performance site placebo controlled study post-doctoral training posters pro-thyrotropin releasing hormone pro-vasopressin prodynorphin proenkephalin professor programs prohormone prolyl oligopeptidase promoter psychosocial pyridostigmine pyroglutamyl-peptidase II racial and ethnic disparities ranpirnase rapid eye movement receptor receptor density reconstitution repository reproductive research and development research study response sample collection sample fixation sarcopenia satisfaction seal serotonin transporter sex sildenafil skills social social movement species difference spine bone structure stem substance abuser success symposium tissue culture tobacco control tool treatment program trend uptake ward

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Drug addiction is now viewed as a brain disease. Understanding the biological basis of substance is needed to develop specific treatment paradigms. The consequences of drug addiction are especially noted in inner city neighborhoods, like the Watts/Willowbrook section of Los Angeles -the catchment area for King/Drew Medical Center. Since addiction is such a complex and devastating illness, a committed public health approach, including education, prevention, treatment and research is needed. Drew University is committed to improvement of the infrastructure needed for substance abuse research, education and treatment. Drew University is well funded for non-substance abuse research and there is a high investigator interest in substance abuse research, yet NIH applications related to drug abuse are deficient. Similar, education on the importance of substance abuse and substance abuse research is lacking on campus. The MIDARP program will provide support to develop the infrastructure needed for substance abuse research at Drew. Thus, the goals of this MIDARP application are to: (1) develop the drug abuse research at Drew; (2) provide research development support and experiences to faculty and staff to facilitate independent drug abuse research careers, (3) foster interest in drug abuse research for students and residents and provide them research experiences, and 4) provide for continued drug abuse research funded by NIDA or other agencies. We will specifically encourage the development of minority faculty and students. The theme of the training and incorporate expertise at Drew The goals of the two research science level and to understand in the reinforcing and addictive projects are to understand the mechanisms of the mechanisms of how the endogenous opioid properties of cocaine.

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