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THE BIOLOGIC EFFECTS OF ANDROGENS IN MEN AND WOMEN

雄激素对男性和女性的生物学影响

基本信息

批准号：
8055261
负责人：
THEODORE C FRIEDMAN
金额：
$ 3.27万
依托单位：
CHARLES R. DREW UNIVERSITY OF MED & SCI
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-05-01 至 2010-09-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8055261
关键词：
Androgens Applications Grants Area Biological Assay Body Composition California Clinical Clinical Research Collaborations Communities Community Services Data Development Education Environment Exercise Physiology Faculty Foundations Funding Future Generations Goals Health Services Research Hormones Institution Laboratories Leadership Link Los Angeles Medicine Minority Minority-Serving Institution Mississippi Molecular Medicine National Institute of Child Health and Human Development Pilot Projects Plant Roots Positioning Attribute Publications Recording of previous events Reproductive Biology Reproductive Endocrinology Reproductive Health Reproductive Medicine Research Research Infrastructure Research Personnel Research Project Grants Rivers Science Scientist Translational Research Universities Woman innovation medical schools meetings men novel programs reproductive

项目摘要

With a longstanding history of collaborations in education, health services research and community service, Drew University, the only historically black medical school west of the Mississippi River, and UCLA, one of this nation's premier universities, are strategically positioned to establish a multi-disciplinary, collaborative, thematicallyfocused and integrated reproductive science research program aimed at studying the biologic effects of androgens in men and women. The Drew-UCLA Reproductive Science Research Center will augment and strengthen the research infrastructure and research capabilities of faculty and trainees at Drew University by supporting the development of several new translational and clinical research projects deemed to be of high priority and significance because of their relevance to reproductive health of men and women. The objectives of this grant proposal - to develop an integrated research program that serves as the foundation for future expansion in reproductive biology, reproductive endocrinology, and reproductive medicine at Drew - are reflected in the following specific aims: 1). Support the implementation of two reproductive science research projects that effectively use the scientific strengths of our institutions, and promote multi-disciplinary approach to the specific research topics in the priority areas identified by this RFA; 2) Provide support for two pilot projects to generate data to facilitate the development of innovative hypotheses and studies, and support the efforts of our investigators to generate preliminary data and publications that can help assure their transition to independent funding; 3) Facilitate and formalize new collaborative networks in reproductive science between scientists at Drew University and UCLA; 4) Develop an Administrative and Planning Core to support the scientific projects. These specific aims will be accomplished by implementing two core research projects and two pilot projects, each having interrelated specific aims consistent with the Center's long-term objectives. The research projects will be supported by an Administrative and Planning Core The proposed core and pilot projects are inter-linked by a common theme, namely, Biologic Effects of Androgens in Men and Women. Energetic program leadership, cross-disciplinary research projects that are thematically-linked and that evolve logically from our current strengths, enthusiastic commitment of bi-institutional support, a large pool of talented, participating faculty, deep historical roots of our institution in the minority communities, and strong infrastructural support from pre-existing Hormone Assay, Body Composition, RCMI Molecular Medicine Core, and Exercise Physiology Core laboratories, and University administration, make our institution particularly suitable to benefit from this NICHD initiative.

在教育、卫生服务研究和社区服务方面有着悠久的合作历史，德鲁大学是密西西比河以西唯一的历史上唯一的黑人医学院，加州大学洛杉矶分校是美国顶尖大学之一，具有战略地位，可以建立一个多学科、协作、以主题为重点的以及旨在研究雄激素对男性和女性的生物影响的综合生殖科学研究计划。德鲁-加州大学洛杉矶分校生殖科学研究中心将通过支持德鲁大学的发展，增强和加强德鲁大学教职员工和实习生的研究基础设施和研究能力一些新的翻译和临床研究项目被认为具有高度优先和重要意义，因为它们与男性和女性的生殖健康有关。这项拨款提案的目标--开发一个综合研究计划，为德鲁大学未来在生殖生物学、生殖内分泌学和生殖医学领域的扩展奠定基础--体现在以下具体目标中：1)。支持实施两个有效利用我们机构科学优势的生殖科学研究项目，并促进对本区域论坛确定的优先领域中的具体研究主题采取多学科方法；2)为两个试点项目提供支持，以产生数据，促进创新研究的发展支持我们的研究人员努力生成初步数据和出版物，以帮助确保他们过渡到独立资助；3)促进并正式确立德鲁大学和加州大学洛杉矶分校科学家之间在生殖科学方面的新合作网络；4)开发一个行政和规划核心，以支持科学项目。这些具体目标将通过实施两个核心研究项目和两个试点项目来实现，每个项目都有与中心长期目标相一致的相互关联的具体目标。这些研究项目将得到一个行政和规划核心的支持。拟议的核心项目和试点项目通过一个共同的主题相互联系，即雄激素对男性和女人。充满活力的项目领导，与主题相关并从我们目前的优势逻辑演变的跨学科研究项目，热情承诺的双机构支持，大量有才华的参与教员，我们机构在少数族裔社区的深厚历史根基，以及强大的来自预先存在的激素分析、身体成分、RCMI分子医学核心、运动生理学核心实验室和大学管理的基础设施支持，使我们的机构特别适合从NICHD倡议中受益。