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THE BIOLOGIC EFFECTS OF ANDROGENS IN MEN AND WOMEN

雄激素对男性和女性的生物学影响

基本信息

批准号：
8055261
负责人：
THEODORE C FRIEDMAN
金额：
$ 3.27万
依托单位：
CHARLES R. DREW UNIVERSITY OF MED & SCI
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-05-01 至 2010-09-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8055261
关键词：
Androgens Applications Grants Area Biological Assay Body Composition California Clinical Clinical Research Collaborations Communities Community Services Data Development Education Environment Exercise Physiology Faculty Foundations Funding Future Generations Goals Health Services Research Hormones Institution Laboratories Leadership Link Los Angeles Medicine Minority Minority-Serving Institution Mississippi Molecular Medicine National Institute of Child Health and Human Development Pilot Projects Plant Roots Positioning Attribute Publications Recording of previous events Reproductive Biology Reproductive Endocrinology Reproductive Health Reproductive Medicine Research Research Infrastructure Research Personnel Research Project Grants Rivers Science Scientist Translational Research Universities Woman innovation medical schools meetings men novel programs reproductive

项目摘要

With a longstanding history of collaborations in education, health services research and community service, Drew University, the only historically black medical school west of the Mississippi River, and UCLA, one of this nation's premier universities, are strategically positioned to establish a multi-disciplinary, collaborative, thematicallyfocused and integrated reproductive science research program aimed at studying the biologic effects of androgens in men and women. The Drew-UCLA Reproductive Science Research Center will augment and strengthen the research infrastructure and research capabilities of faculty and trainees at Drew University by supporting the development of several new translational and clinical research projects deemed to be of high priority and significance because of their relevance to reproductive health of men and women. The objectives of this grant proposal - to develop an integrated research program that serves as the foundation for future expansion in reproductive biology, reproductive endocrinology, and reproductive medicine at Drew - are reflected in the following specific aims: 1). Support the implementation of two reproductive science research projects that effectively use the scientific strengths of our institutions, and promote multi-disciplinary approach to the specific research topics in the priority areas identified by this RFA; 2) Provide support for two pilot projects to generate data to facilitate the development of innovative hypotheses and studies, and support the efforts of our investigators to generate preliminary data and publications that can help assure their transition to independent funding; 3) Facilitate and formalize new collaborative networks in reproductive science between scientists at Drew University and UCLA; 4) Develop an Administrative and Planning Core to support the scientific projects. These specific aims will be accomplished by implementing two core research projects and two pilot projects, each having interrelated specific aims consistent with the Center's long-term objectives. The research projects will be supported by an Administrative and Planning Core The proposed core and pilot projects are inter-linked by a common theme, namely, Biologic Effects of Androgens in Men and Women. Energetic program leadership, cross-disciplinary research projects that are thematically-linked and that evolve logically from our current strengths, enthusiastic commitment of bi-institutional support, a large pool of talented, participating faculty, deep historical roots of our institution in the minority communities, and strong infrastructural support from pre-existing Hormone Assay, Body Composition, RCMI Molecular Medicine Core, and Exercise Physiology Core laboratories, and University administration, make our institution particularly suitable to benefit from this NICHD initiative.

在教育，卫生服务研究和社区服务方面有着悠久的合作历史，德鲁大学是密西西比河以西唯一一所历史悠久的黑人医学院，加州大学洛杉矶分校是这个国家的主要大学之一，他们的战略定位是建立一个多学科，合作，主题集中的以及旨在研究雄激素对男性和女性的生物学影响的综合生殖科学研究计划。德鲁-加州大学洛杉矶分校生殖科学研究中心将通过支持以下方面的发展，扩大和加强德鲁大学教师和学员的研究基础设施和研究能力：若干新的转化和临床研究项目被视为高度优先和重要的项目，因为它们与男女生殖健康有关。这项拨款提案的目标-开发一个综合研究计划，作为未来扩展生殖生物学，生殖内分泌学和生殖医学的基础-反映在以下具体目标中：1）。支持推行两项生殖科学研究计划，以有效运用院校的科研力量，并推动以跨学科方法研究本研究纲领所确定的优先研究范畴内的特定研究课题; 2）支持两项试验计划，以产生数据，促进发展创新我们的研究人员的努力，以产生初步的数据和出版物，可以帮助确保他们过渡到独立的资金; 3）促进和正式化在生殖科学在德鲁大学和加州大学洛杉矶分校的科学家之间的新的合作网络; 4）开发一个行政和规划核心，以支持科学项目。这些具体目标将通过实施两个核心研究项目和两个试点项目来实现，每个项目都有与中心的长期目标相一致的相互关联的具体目标。这些研究项目将得到行政和规划核心的支持。拟议的核心项目和试点项目由一个共同的主题联系在一起，即雄激素对男性的生物学影响，妇女充满活力的计划领导，跨学科的研究项目，这些项目是主题相关的，并从我们目前的优势，热情的承诺，双机构的支持，大量的人才，参与教师，我们的机构在少数民族社区的深厚历史根源，以及强大的来自现有激素测定，身体成分，RCMI分子医学核心和运动生理学核心实验室以及大学管理部门的基础设施支持，使我们的机构特别适合从NICHD计划中受益。