PHYSIOLOGY AND PATHOPHYSIOLOGY OF BASAL GANGLIA IN PARKINSON?S DISEASE

帕金森病基底节的生理学和病理生理学

• 批准号: 7349428
• 负责人: Erwin B. Montgomery
• 金额: $ 2.72万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7349428
• 关键词: PHYSIOLOGY; PATHOPHYSIOLOGY; BASAL; GANGLIA; PARKINSON

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To use rhesus monkey (Macaca mulatta) models of Parkinsonism and deep brain stimulation (DBS) as a way to probe how the basal ganglia and the motor and sensory cortex act as a functioning unit. The laboratory is now fully functional. We have developed new technologies and methodologies for data accusation and analysis. Microelectrode recordings in the basal ganglia-thalamic-cortical system in a behaving rhesus monkey. This research used WNPRC Animal Services and WNPRC Operational Services (Shop).

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。利用猕猴（Macaca mulatta）帕金森模型和深部脑刺激（DBS）作为一种方法来探索基底神经节和运动和感觉皮层如何作为一个功能单元发挥作用。实验室现在功能齐全。我们已经开发了新的数据指控和分析技术和方法。行为猕猴基底神经节-丘脑-皮质系统的微电极记录。本研究使用WNPRC动物服务和WNPRC运营服务（商店）。