Strength Training Using NMES for Children With CP

使用 NMES 对 CP 儿童进行力量训练

基本信息

批准号：
7409990
负责人：
SAMUEL C.K. LEE
金额：
$ 28.41万
依托单位：
UNIVERSITY OF DELAWARE
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-07-01 至 2009-09-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7409990
关键词：
Activities of Daily Living Adult Affect Ankle Area Brain Diseases Cerebral Palsy Characteristics Child Clinical Congenital Abnormality Control Groups Development Economics Electric Stimulation Electromyography Exercise Fatigue Fire - disasters Functional disorder Gait Generations Goals Hypertrophy Image Impairment Injury Isometric Exercise Knee Little&apos s Disease Lower Extremity Magnetic Resonance Imaging Measures Medical Care Costs Metabolic Motor Muscle Neuraxis Neurologic Numbers Operative Surgical Procedures Orthopedics Oxygen Consumption Physiological Population Production Property Rate Rehabilitation therapy Research Score Skeletal Muscle Spastic Spinal cord injury Stroke Surface Techniques Thinking Time Training Programs Triceps Brachii Muscle Upper Extremity Walking Week Work base cost design improved motor impairment muscle hypertrophy muscle strength programs rehabilitation strategy spatiotemporal strength training

项目摘要

DESCRIPTION (provided by applicant): Cerebral palsy (CP) has the highest lifetime economic cost and net cost of medical care compared to the most common birth defects. Reduced muscle strength affects functional abilities in children with CP. Volitional strength training in children with CP can produce substantial gains in force production with concomitant gains in function. Volitional strength training, however, may not be optimal for producing strength gains in this population due to reduced voluntary muscle activation. Neuromuscular electrical stimulation (NMES) activates a greater number of motor units and produces higher firing rates of the active motor units than can be obtained volitionally. Thus, NMES may offer advantages over volitional exercise programs for producing gains in force production. The proposed research is designed to develop improved rehabilitation techniques for children with CP. This study compares the effects of a 12-week NMES isometric strength-training program to 12 weeks of traditional isometric strength training in children with CP. A no-exercise control group with CP will also be studied. The specific aims are: 1) To compare the force generating, volitional activation, contractile and fatigue characteristics of the quadriceps femoris and triceps surae muscles in typically developing children and children with CP; 2) to assess the ability of NMES strength training to increase quadriceps femoris and triceps surae muscle force-generating ability as compared to volitional strength training and a no-exercise control group in children with CP; 3) to assess the mechanisms underlying improvements in force-generating ability of the quadriceps femoris and triceps surae after strength training in children with CP; and 4) to assess the ability of strength training to improve gross motor function and gait in children with CP. This work will help clinicians design rehabilitation strategies based on the physiologic differences in skeletal muscle and mechanisms for force production between children with CP and children of typical development. Increasing muscle force-generating ability of children with CP can improve a child's function during activities such as sitting, standing and walking.

描述（由申请人提供）：与最常见的先天缺陷相比，脑瘫（CP）的终身经济成本和净成本最高。肌肉力量降低会影响CP儿童的功能能力。 CP儿童的自愿性训练可以在功能中带来巨大的力量产生增长。但是，由于自愿肌肉激活减少，自愿训练可能并不是在该人群中产生强度增长的最佳选择。神经肌肉电刺激（NME）激活更多的电动机单元，并产生活性电动机单元的发射速率高于自愿性。因此，NME可能会提供优于自愿性锻炼计划，以产生力生产收益。拟议的研究旨在为CP儿童开发改进的康复技术。这项研究比较了为期12周的NMES等轴测强度训练计划与CP儿童的传统等轴测强度训练的影响。还将研究一个具有CP的无运动控制组。具体目的是：1）比较股股四头肌和三头肌肌肉的产生力，自愿性激活，收缩和疲劳特征。 2）评估NMES力量训练的能力增加了股股四头肌和三头肌的肌肉肌肉产生能力，与意志力训练和CP儿童的无运动对照组相比； 3）评估在CP儿童的力量训练后，股股骨肌和三头肌的力量的改善机制； 4）评估力量训练改善CP儿童总体运动功能和步态的能力。这项工作将帮助临床医生根据骨骼肌的生理差异以及CP儿童与典型发育儿童之间的力量生产的生理差异来设计康复策略。在坐着，站立和步行等活动期间，增加CP儿童的肌肉力量产生能力可以改善孩子的功能。

项目成果

期刊论文数量（12）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

The relationship between spasticity and muscle volume of the knee extensors in children with cerebral palsy.

脑瘫患儿膝关节伸肌痉挛与肌肉量的关系

DOI：
10.1097/pep.0b013e31824cc0a9
发表时间：
2012
期刊：
Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association
影响因子：
0
作者：
Pierce,SamuelR;Prosser,LauraA;Lee,SamuelCK;Lauer,RichardT
通讯作者：
Lauer,RichardT

Comparison of techniques to determine human skeletal muscle voluntary activation.

确定人体骨骼肌自主激活的技术比较。

DOI：
10.1016/j.jelekin.2017.05.011
发表时间：
2017
期刊：
Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology
影响因子：
0
作者：
Zarkou,Anastasia;Stackhouse,Scott;Binder-Macleod,StuartA;Lee,SamuelCK
通讯作者：
Lee,SamuelCK

The effects of a shank guide on cycling biomechanics of an adolescent with cerebral palsy: a single-case study.

小腿导向器对脑瘫青少年自行车生物力学的影响：单例研究。

DOI：
10.1016/j.apmr.2008.03.010
发表时间：
2008
期刊：
Archives of physical medicine and rehabilitation
影响因子：
4.3
作者：
Johnston,ThereseE;Lauer,RichardT;Lee,SamuelC
通讯作者：
Lee,SamuelC

Trunk and hip muscle activity in early walkers with and without cerebral palsy--a frequency analysis.

DOI：
10.1016/j.jelekin.2010.04.005
发表时间：
2010-10
期刊：
JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY
影响因子：
2.5
作者：
Prosser, Laura A.;Lee, Samuel C. K.;Barbe, Mary F.;VanSant, Ann F.;Lauer, Richard T.
通讯作者：
Lauer, Richard T.

Biomechanics of recumbent cycling in adolescents with cerebral palsy with and without the use of a fixed shank guide.

脑瘫青少年在使用和不使用固定小腿导向器的情况下卧式骑自行车的生物力学。