A metabolomic approach to the identification of health based consumer traits in tomato

鉴定番茄健康消费者特征的代谢组学方法

• 批准号: BB/D00716X/1
• 负责人: Peter Bramley
• 金额: $ 36.91万
• 依托单位: Royal Holloway University of London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FD00716X%2F1
• 关键词: metabolomic; approach; identification; health; based

We want to eat nice, tasty fruit and vegetables that are safe and good for us. Antioxidants are compounds found in fruits and vegetables that when obtained in the diet can help combat diseases. This is why it is important to eat fruits and vegetables regularly. In order to create improved, nutritional fruit and vegetables breeding programmes must be carried out to incorporate the desired improvements from one variety into another, which already has other worthwhile qualities. This approach utilises natural diversity and is a non-GM approach, thus avoiding the incorporation of foreign DNA. It is the composition of the molecules (chemicals) in the fruit that yield the characteristic properties we want. In order to identify improved health features and other characteristics that we want the molecules of interest have to be analysed. Modern methods enable us to identify many molecules simultaneously. We will use these chemical approaches to identify tomato varieties with improved features, especially those that will improve our health. To do this tomato collections that have had diversity crossed into a parent will be used. The amounts and types of compounds identified will be large and using computational approaches, these molecules can be linked to the desired characteristics we need to have in the final variety. In our case, this will be an enhanced level of antioxidants.

我们想吃美味可口的水果和蔬菜，这些水果和蔬菜对我们既安全又有益。抗氧化剂是在水果和蔬菜中发现的化合物，当从饮食中获得时可以帮助对抗疾病。这就是为什么定期吃水果和蔬菜很重要。为了创造更好的营养水果和蔬菜育种计划，必须将一个品种所需的改进纳入另一个品种，后者已经具有其他值得的品质。这种方法利用自然多样性，是一种非转基因方法，从而避免了外来DNA的掺入。正是水果中分子（化学物质）的组成产生了我们想要的特性。为了确定改善的健康特征和我们想要的其他特征，必须分析感兴趣的分子。现代方法使我们能够同时识别许多分子。我们将使用这些化学方法来识别具有改进功能的番茄品种，特别是那些将改善我们健康的品种。为了做到这一点，将使用具有多样性的番茄收集物与亲本杂交。所鉴定的化合物的数量和类型将很大，使用计算方法，这些分子可以与我们需要在最终品种中具有的所需特征相关联。在我们的情况下，这将是一个增强的抗氧化剂水平。

项目成果

A genome-wide metabolomic resource for tomato fruit from Solanum pennellii.

• DOI: 10.1038/srep03859
• 发表时间: 2014-01-24
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Perez-Fons L;Wells T;Corol DI;Ward JL;Gerrish C;Beale MH;Seymour GB;Bramley PM;Fraser PD
• 通讯作者: Fraser PD