PHARMACOGENIC REASONS FOR POOR LUPUS NEPHRITIS OUTCOMES

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to determine whether genetic make-up of certain CYP450 enzymes are significant in predicting responses (in terms of improved kidney function) to cyclophosphamide and glucocorticoid therapy.