PHARMACOGENIC REASONS FOR POOR LUPUS NEPHRITIS OUTCOMES

狼疮性肾炎预后不良的药理学原因

• 批准号: 7625587
• 负责人: MELANIE S JOY
• 金额: $ 1.84万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7625587
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Cyclophosphamide; Enzymes; Funding; Genetic; Glucocorticoids; Grant; Institution; Lupus Nephritis; Outcome; Purpose; Renal function; Research; Research Personnel; Resources; Source; United States National Institutes of Health; improved; research study; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to determine whether genetic make-up of certain CYP450 enzymes are significant in predicting responses (in terms of improved kidney function) to cyclophosphamide and glucocorticoid therapy.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究的目的是确定某些CYP450酶的遗传组成在预测对环磷酰胺和糖皮质激素治疗的反应（以改善的肾脏功能）方面是否重要。