ANTIPHOSPHOLIPID SYNDROME COLLABORATIVE REGISTRY

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。目的：本研究的目的是建立抗磷脂综合征（APS）的国家登记处。登记研究将收集和更新APS患者和无症状抗磷脂抗体患者的临床、人口统计学和实验室数据。 研究方法和方法：在为期5年的研究中，8个研究中心预计每年招募50名患者。参与者将接受约30-45分钟的访谈，以获得有关APS病史和特征的详细信息。将采集并储存血液样本，以确认是否存在抗磷脂抗体。一旦受试者被批准入组，可能会就涉及登记研究的未来研究与他们联系。参与者没有义务参与这些研究。 研究进展：本研究目前在圣安东尼奥研究中心入组了79例受试者。目前，我们完成了15次两年随访。在全国范围内，登记册刚刚超过一半，并已开始接受审查协议。一旦接受，这些研究将联系当地研究中心，并可供合格患者入组。 目的：本研究的目的是建立抗磷脂综合征（APS）的国家登记处。登记研究将收集和更新APS患者和无症状抗磷脂抗体患者的临床、人口统计学和实验室数据。 研究方法和方法：在为期5年的研究中，8个研究中心预计每年招募50名患者。参与者将接受约30-45分钟的访谈，以获得有关APS病史和特征的详细信息。将采集并储存血液样本，以确认是否存在抗磷脂抗体。一旦受试者被批准入组，可能会就涉及登记研究的未来研究与他们联系。参与者没有义务参与这些研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. OBJECTIVE: The purpose of this study is to establish a national registry for Antiphospholipid Syndrome (APS). The registry will collect and update clinical, demographic, and update clinical, demographic, and laboratory data on individuals with APS and asymptomatic patients with antiphospholipid antibodies. RESEARCH PLAN AND METHODS: Each of the eight sites are expected to enroll 50 patients per year of the 5-year study. Participants will be interviewed for approximately 30-45 minutes to get detailed information about medical history and features of APS. A blood sample will be obtained and stored for confirmation of the presence of antiphospholipid antibodies. Once the participant has been approved for enrollment they may be contacted about future studies involving the registry. Participants are under no obligation to participate in these studies. STUDY PROGRESS: This study currently has 79 people enrolled at the San Antonio site. We completed 15 two year f/u visits at the present time. Nationally, the registry is just over half full and has begun to accept protocols for review. Once accepted these studies will contact local sites and be available for eligible patient enrollment. OBJECTIVE: The purpose of this study is to establish a national registry for Antiphospholipid Syndrome (APS). The registry will collect and update clinical, demographic, and update clinical, demographic, and laboratory data on individuals with APS and asymptomatic patients with antiphospholipid antibodies. RESEARCH PLAN AND METHODS: Each of the eight sites are expected to enroll 50 patients per year of the 5-year study. Participants will be interviewed for approximately 30-45 minutes to get detailed information about medical history and features of APS. A blood sample will be obtained and stored for confirmation of the presence of antiphospholipid antibodies. Once the participant has been approved for enrollment they may be contacted about future studies involving the registry. Participants are under no obligation to participate in these studies.