SALUD BONE MINERAL DENSITY SUB-STUDY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 这是一个子研究的母研究，题为“临床和血清学预测神经精神系统性红斑狼疮。“SALUD研究的这项子研究的总体目标是评估骨矿物质密度如何随着疾病的严重程度和进展以及药物治疗而变化。 还将收集有关营养摄入（包括抗氧化剂）的信息，以确定营养的潜在病因作用。 之前入组SALUD研究的受试者将有资格参加本子研究。 每个人都将进入GCRC进行骨矿物质密度测量、完成营养和身体活动评估问卷以及生物样本收集。 研究程序将每年重复一次。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a sub-study to the parent study titled, "Clinical and Serologic Predictors of Neuropsychiatric SLE." The overall aim of this sub-investigation of the SALUD study is to assess how bone mineral density changes with disease severity and progression, as well as with medical treatment. Information regarding nutritional intake, including antioxidants, will also be collected to determine the potential etiologic role of nutrition. Previously enrolled participants in the SALUD study will be eligible for participation in this sub-study. Each will be admitted to the GCRC for bone mineral densitometry, completion of nutritional and physical activity assessment questionnaires, and biologic samples collection. The research procedures will be repeated annually.