INFLUENZA VACCINATION IN RENAL TRANSPLANT RECIPIENTS ON RAPAMYCIN

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项研究比较了服用雷帕霉素方案的肾移植受者和非服用雷帕霉素方案的肾移植受者对流感疫苗的免疫反应。从马萨诸塞州总医院和贝丝-以色列女执事医疗中心招募的两支部队中，每支部队都将有大约30名志愿者。这将是一项观察性的门诊研究。它需要两次学习访问(总共)和少量抽血。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study compares immune responses to influenza vaccination in renal transplant recipients who are on a rapamycin regimen with those who are on a non-rapamycin regimen. Approximately 30 volunteers would be in each of the two arms, recruited from the Massachusetts General Hospital and the Beth-Israel Deaconess Medical Center. This will be an obervational outpatient study. It requires two study visits (total) and small volume blood draws.